Transaction in Own Shares

GlaxoSmithKline PLC
02 December 2004



                              GlaxoSmithKline PLC


GlaxoSmithKline plc (the "Company") announces that in accordance with the
authority granted by shareholders at the Company's Annual General Meeting on 17
May 2004 it purchased 890,000 of it's Ordinary shares of 25 pence each ("shares
") on 2 December 2004 at a price of 1124.75 pence per share.



The Company intends to hold these shares in Treasury.



Following the purchase of these shares, the Company holds 59,748,000 of it's
shares in Treasury and has 5,877,213,323 shares in issue (excluding Treasury
shares).



This announcement does not constitute, or form part of, an offer or any
solicitation of an offer to purchase or subscribe for securities in any
jurisdiction.





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