Interim Results

RNS Number : 8856R
Immupharma PLC
27 September 2017
 

 

FOR IMMEDIATE RELEASE

27 SEPTEMBER 2017

 

 

ImmuPharma PLC

("ImmuPharma" or the "Company")

 

INTERIM RESULTS ANNOUNCEMENT
for the six months ended 30 June 2017

 

ImmuPharma PLC (LSE:IMM), ("ImmuPharma" or the "Company"), the specialist drug discovery and development company, is pleased to announce its interim results for the six months ended 30 June 2017 (the "Period").

 

Key Highlights

 

·     Lupuzor: is the Company's lead program for the potential breakthrough compound for Lupus a potential life threatening auto-immune disease

§ Total 11 sites active in US with 70 patients

§ Five European countries with 81 Lupus patients taking part in the trial: Czech Republic, France, Germany, Hungary and Poland

§ One Mauritius site with 49 Lupus patients included in trial

 

·    Most recent update on progress of Lupuzor™ trial announced on 21 September 2017

·     Top line results on track to report in Q1 2018

·     As announced on 26 September 2017, first steps initiated for Lupuzor's™ regulatory submissions

 

·     £4.1 million fundraising (before expenses) successfully completed in March 2017

 

·     Northland Capital Partners appointed as sole broker and NOMAD

·     Stable financial performance over the Period, in line with market expectations

Net assets of £6.4 million (31 December 2016: £5.5 million)

Loss for the Period of £3.0 million (H1 2016:  £3.7million)

§ Research and Development expenses of £2.3 million (H1 2016: £2.5 million)

Basic and diluted loss per share of 2.34p (H1 2016: 3.35p)

·     New employee share option plan implemented in March 2017 to continue to attract and retain key individuals

 

·     'Investor' Event on 30 June 2017

ImmuPharma successfully hosted a technology symposium on Friday 30 June following the Company's AGM. The event attended by institutional and private investors included presentations from key management on the three core technology platforms. The video of the presentation can be seen on http://www.immupharma.co.uk/media/events

 

·     New ImmuPharma website launched:  www.immupharma.co.uk

 

Commenting on the Interims and outlook Tim McCarthy, Chairman, said:

 

"Ensuring that our pivotal Phase III Lupuzor™ trial progresses on track remains a key focus for ImmuPharma.

 

"We recently announced that all patients in the study have now passed the six months stage, with over 26% of patients having now completed the full 12 months.  With a continued robust safety record, we are looking forward with confidence and planning for a successful outcome of the study with all patients completing the treatment protocol in the coming months and to reporting top-line results in Q1 2018.

 

"Having successfully completed a £4.1 million fundraising (before expenses) in March, the Board would like to thank its shareholders for their continued support, as well as its staff, corporate and scientific advisors and the CNRS for their ongoing collaboration."

 

This announcement contains inside information for the purposes of Article 7 of Regulation (EU) 596/2014. ("MAR")

 

 

For further information please contact:

ImmuPharma plc

+ 44 (0) 20 7152 4080

Tim McCarthy, Chairman


Dimitri Dimitriou, Chief Executive Officer

Dr Robert Zimmer, President and CSO


Tracy Weimar, Vice President, Operations and Finance


Lisa Baderoon, Head of Investor Relations

+ 44 (0) 7721 413496



Northland Capital Partners Limited, Joint Broker

+44 (0) 20 3861 6625

Patrick Claridge, David Hignell, Jamie Spotswood Corporate Finance


Rob Rees, Corporate Broking


 

 

 

 

 

 

 

 

 



ImmuPharma plc

Chairman's Statement

 

INTERIM HIGHLIGHTS

 

The first half of 2017 saw the continued progression of our lead program LupuzorTM, for the treatment of Lupus, through significant milestones in its pivotal Phase III trial. The most recent update to the trial as announced on 21 September 2017 confirmed that as at 15 September 2017:

 

all patients in the study have passed the 6 months stage, and

52 patients (26%) have completed the full 12 months of the study

Importantly there continues to be a robust safety record which remains consistent with Lupuzor™'s product profile as shown in its previous Phase IIb study.

 

As announced on 26 September 2017, with the trial progressing on track, ImmuPharma is planning ahead in anticipation of the trial's successful outcome. In consultation with our regulatory advisors, we are now progressing the completion of the regulatory dossiers in preparation for submission to the Food and Drug Administration (FDA) and the European Medicines Agency (EMA).  This includes the finalisation of the Drug Master File (DMF) and in particular the manufacture of commercial batches of the LupuzorTM drug.  These will be manufactured according to described procedures in the DMF, to be ready for inclusion in the Company's regulatory submissions. ImmuPharma expects to have the first set of batches ready by the end of Q1 2018 in line with Lupuzor'sTM Phase III top line results being announced. 

 

We were also pleased to have successfully completed an oversubscribed £4.1 million fundraising (before expenses) in March 2017. The funds raised strengthened the Company's Statement of Financial Position and have also supported further investment in ImmuPharma's earlier stage portfolio, in particular its P140 peptide platform.

 

 

Lupuzor™ Phase III Trial - Progress through H1 2017

 

Lupuzor received approval from the US Food and Drug Administration (FDA) to start Phase III with a Special Protocol Assessment (SPA) and Fast Track designation, perceived as the 'Gold Standard' from the FDA. Under the SPA, the necessary number of patients for the Phase III programme is much lower than other Lupus development candidates in previous clinical trials and underpins the significant efficacy and safety profile shown by Lupuzor in its clinical development program to date.  Importantly, this means that the total cost and time to completion of Phase III is significantly reduced.

 

The Phase III trial is a double-blind, randomised, placebo-controlled trial. The study involves patients being dosed for one year, receiving 0.2mg once every month subcutaneously. Significant progress was made toward completion of the trial.  293 patients were screened illustrating the demand from physicians for a new, safe and effective treatment for Lupus.  Of these, the required 200 patients have been successfully recruited and randomised (dosed).  Patients are participating in the trial in 7 countries across 28 sites. 

 

In the United States the trial has been approved by a major Central Institutional Review Board (IRB) which is allowing several sites to participate through a single IRB. In Europe, the study is approved through the centralised Voluntary Harmonisation Procedure (VHP).  Through the EU VHP the study is taking place in Germany, France, Czech Republic, Hungary and Poland.

 

ImmuPharma was also requested to open a new site in Mauritius.  CAP Research, a major clinical research organisation in Mauritius, is leading the trial and 49 patients have been recruited.  Mauritius, with a population of around 1.2 million, has a high proportion, approximately 300 of Lupus patients currently diagnosed. Top line data is expected during Q1 2018.  Progress of the trial can be seen at: www.clinicaltrials.gov (search term 'Lupuzor').

 

Lupus - Opportunity

 

There are an estimated five million people globally suffering from Lupus, with approximately 1.5 million patients in the US, Europe and Japan (Source: Lupus Foundation of America). Current 'standard of care' treatments, including steroids and immunosuppressants, can potentially have either serious side effects for patients or limited effectiveness, with over 60% of patients not adequately treated. GSK's Benlysta is the first Lupus drug approved in many years and paves the path to market for Lupuzor™. Based on conservative estimates, and taking into account that Benlysta is priced currently at approximately US$30,000 per patient per year, Lupuzor™ would be entering a market with the potential for multi-billion dollar sales.

 

Lupuzor™ has the potential to be a novel specific first-line drug therapy for the treatment of Lupus by specifically modulating the immune system and halting disease progression in a substantial proportion of patients. Lupuzor™ has a unique mechanism of action that modulates the activity of CD4 T-cells which are involved in the cell-mediated immune response which leads to the Lupus disease. Lupuzor™, taken over the long term, as indicated in earlier stage clinical trials, has the potential to prevent the progression of Lupus rather than just treating its symptoms, with the rest of the immune system retaining the ability to work normally.

 

There will be a number of routes to market for Lupuzor™ which could include: a global licensing deal; ImmuPharma partnering with regional distributors, or an outright sale of Lupuzor™ or the Company. The prime objective of any strategy would be to maximise shareholder return. 

 

Pipeline Overview

 

LupuzorTM - Forigerimod / P140 Auto-Immune Platform

 

Lupuzor™, is also known by its chemical name 'Forigerimod' or P140.

 

ImmuPharma, in conjunction with the CNRS, is working hard on expanding the P140 auto immune pipeline, which is supported by Lupuzor's strong efficacy and safety profile and by its mechanism of action.

 

An important patent has been granted in key countries (USA, EU, China, India and Japan) covering LupuzorTM up to 2032 and its use in the treatment of a majority of autoimmune diseases such as Sjogrens, rheumatoid arthritis, Crohn's and CIDP.

 

Additionally, a new patent has been filed (co-owned with CNRS) to cover non-autoimmune indications. Further preclinical work continues at the CNRS with the objective of further indications moving into the clinic in due course.

 

Nucant Platform

 

Our Cancer Nucant program, IPP-204106, is focused on combination therapy approaches and ImmuPharma is reviewing a number of options to further progress this program.  In 2016, a grant was awarded by the EU to different EU partners (€7 million total with €430k awarded to ImmuPharma) to develop the Nucants in combination with cytotoxic drugs linked to a solid support.  The concept has been validated in pre-clinical studies.  As indicated in many high-level scientific journals (Cancer Research), Nucants can be used to selectively target cancer cells and deliver on target highly cytotoxic drugs.  Further, it has been proven that Nucants are drastically enhancing the effects of cytotoxic drugs at the tumour level (factor 3) allowing thereby improved efficacy and/or reduction of side effects for the same efficacy.  The product, subject to funding, is ready for Phase II development.

 

The Group has also been awarded grants to investigate its use in age-related macular degeneration, diabetic retinopathy and other ophthalmological indications.  The preliminary results are very encouraging and the product could be ready for clinical assessment provided sufficient funding is secured.

 

Peptide Platform

 

ImmuPharma's subsidiary 'Ureka' has initiated the development of a novel and innovative peptide technology platform through the Company's collaboration with CNRS, thereby gaining access to pioneering research centred on novel peptide drugs at the University of Bordeaux and the Institut Européen de Chimie et Biologie (IECB). Jointly, ImmuPharma and CNRS have filed a new co-owned patent controlling this breakthrough peptide technology. The first therapeutic area being targeted is diabetes with glucagon-like peptide -1 agonists, a class of drugs for the treatment of diabetes, as well as initiating the development of novel peptides as glucagon antagonists - one of the novel approaches to treat Type I and Type II diabetes.  A consequence of this approach is the development of long acting peptides to treat NASH (Non-Alcoholic Steato-Hepatitis), one of the most important challenges for public health in the future.  ImmuPharma has received non-refundable grants of approximately €600,000 to develop this technology with application to peptides used to treat diabetes as well as to peptides which allow the control of protein/protein interactions (cancer, targeting P53 interactions).

 

Investor Symposium on 30 June 2017

 

ImmuPharma held a technology symposium in London on 30 June 2017 following the Company's AGM. Over forty investors attended the event which included both institutions and private investors. The key objective of the event was to give further insight into ImmuPharma's three core technology platforms:

·     Lupuzor™ / P140 : Auto Immune Diseases

·     Nucants : Oncology / Opthamology

·     Peptides : Metabolic Disorders

Vadim Alexandre, Healthcare Analyst at Northland Capital Partners also provided his view on the investment case for ImmuPharma centred on Lupuzor™, an overview of the Auto-Immune sector and competitive landscape.

 

The video of the presentation can be seen on http://www.immupharma.co.uk/media/events.

 

Financial Review

 

ImmuPharma's cash balance at 30 June 2017 was £3.13 million (£1.88 million at 31 December 2016, £0.66 million at 30 June 2016).  Further to the Lanstead sharing agreement entered into in February 2016, the Company also has £0.94 million as a derivative financial asset (£1.55 million at 31 December 2016, £3.14 million at 30 June 2016).  The sharing agreement with Lanstead includes the provision for 18 monthly tranches of proceeds from the derivative financial asset depending on the share price performance versus an agreed benchmark price.  At 30 June 2017, there were 3 monthly tranches outstanding, therefore the sharing agreement will shortly be coming to an end. The Company also has an asset in respect of a prepayment of £0.80 million of advanced fees to Simbec-Orion at 30 June 2017 (£1.24 million at 31 December 2016, £1.75 million at 30 June 2016).  Basic and diluted loss per share were 2.34p and 2.34p respectively (30 June 2016: 3.35p and 3.35p).  In line with the Company's current policy, no interim dividend is proposed.

 

Operating loss for the Period was £3.2 million (£3.2 million for the six months ended 30 June 2016).  Research and development expenditure in the Period was £2.3 million (£2.5 million for the six months ended 30 June 2016) reflecting primarily the significantly increased expenditure related to the LupuzorTM Phase III clinical trial.  Administrative expenses were £0.93 million during the Period (£0.73 million for the six months ended 30 June 2016).

 

Given the stage of ImmuPharma's development, the fact that losses have continued to be made is to be expected since there is minimal revenue and business activity is concerned with significant investment in the form of clinical trial expenditure in addition to maintaining the infrastructure of the Group.

 

Current Activities and Outlook

 

The Board are excited by ImmuPharma's medium and long term potential. We are focused on the late stage clinical development of Lupuzor through its pivotal Phase III trial and are looking forward with confidence to announcing top-line data by the end of the first quarter of 2018. We will also continue to communicate on a regular basis with shareholders as this trial progresses.

 

ImmuPharma will also continue to look at ways to create further value in its assets as it progresses its other earlier stage pipeline candidates whilst exploring other opportunities around Lupuzor's mechanism of action and its applicability to other autoimmune conditions.

 

The Board would like to thank its shareholders, both longstanding and those who participated in the more recent fundraisings, for their support as well as its staff, corporate and scientific advisers including Simbec-Orion and the CNRS for their continued collaboration.

 

 

 

 

 

Tim McCarthy                                   

Chairman         

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

ImmuPharma plc

 

CONSOLIDATED INCOME STATEMENT

FOR THE PERIOD ENDED 30 JUNE 2017

 

 

 

 

 

Note

Unaudited

6 months ended

30 June 2017

 

Audited

Year

 ended 31 December

2016

 

Unaudited

6 months ended

30 June 2016

 

 

£

 

£

 

£

Continuing operations

 

 

 

 

 

 

Revenue

1

       86,504

 

164,784

 

2,924

Research and development expenses

 

 (2,345,815)

 

(5,267,087)

 

(2,508,578)

Administrative expenses

 

(927,640)

 

(1,486,858)

 

(733,893)

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Operating loss

 

(3,186,951)

 

(6,589,161)

 

(3,239,547)

 

 

 

 

 

 

 

Finance costs

 

(375)

 

(23,085)

 

(501,671)

Finance income

 

153,915

 

297,809

 

362

 

 

 

 

 

 

 

 

 


 

 

 


Loss before taxation

 

(3,033,411)

 

(6,314,437)

 

(3,740,856)

 

 

 

 

 

 

 

Tax

 

(485)

 

990,421

 

(362)

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Loss for the period

 

(3,033,896)

 

(5,324,016)

 

(3,741,218)

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Attributable to:

 

 

 

 

 

 

Equity holders of the parent company

 

(3,033,896)

 

(5,324,016)

 

(3,741,218)

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Loss per ordinary share

 

 

 

 

 

 

 

 

 

 

 

 

 

Basic

2

(2.34)p

 

(4.54)p

 

(3.35)p

 

 

 

 

 

 

 

 

Diluted

2

(2.34)p

 

(4.54)p

 

(3.35)p

 

 

 

 

 

 

 

 

 

 


ImmuPharma plc

 

CONSOLIDATED STATEMENT OF COMPREHENSIVE INCOME
FOR THE PERIOD ENDED 30 JUNE 2017

 

 

 

Unaudited

6 months ended

30 June

 2017

 

Audited

Year

 ended 31 December

2016

 

Unaudited

6 months ended

30 June

 2016

 

£

 

£

 

£

 

 

 

 

 

 

Loss for the financial period

(3,033,896)

 

(5,324,016)

 

(3,741,218)

 

 

 

 

 

 

 


 

 

 


Other comprehensive income

 

 

 

 

 

Items that may be reclassified subsequently to profit or loss:

 

 

 

 

 

 

Exchange differences on translation of foreign operations


(56,133)

 


317,177

 


224,692

 

 

 

 

 

 

 

 

 

 

 

 

Total items that may be reclassified subsequently to profit or loss

(56,133)

 

317,177

 

224,692

 

 

 

 

 

 

Other comprehensive loss for the period

 

(56,133)

 


317,177

 


224,692

 

 

 

 

 

 

 

 

 

 

 

 

Total comprehensive loss for the period

(3,090,029)

 

(5,006,839)

 

(3,516,526)

 

 

 

 

 

 

 

 

 

 

 


ImmuPharma plc

 

CONSOLIDATED STATEMENT OF FINANCIAL POSITION

AS AT 30 JUNE 2017

 

 

Note

Unaudited

30 June

2017

 

Audited

31 December

2016

 

Unaudited

30 June 2016

 

 

 

£

 

£

 

£

 

Non-current assets

 

 

 

 

 

 

 

Intangible assets

 

497,585

 

511,088

 

522,668

 

Property, plant and equipment

 

192,573

 

231,901

 

269,435

 

Derivative financial asset

4

-

 

-

 

587,054

 

 

 

 

 

 

 

 

 

 

 


 

 

 


 

Total non-current assets

 

690,158

 

742,989

 

1,379,157

 

 

 

 

 

 

 

 

 

 

 


 

 

 


 

Current assets

 

 

 

 

 

 

 

Trade and other receivables

 

2,439,143

 

       2,535,265

 

2,724,631

 

Derivative financial asset

4

943,861

 

1,554,866

 

2,556,565

 

Cash and cash equivalents

 

3,131,595

 

1,876,718

 

661,009

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Total current assets

 

6,514,599

 

5,966,849

 

5,942,205

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Current liabilities

 

 

 

 

 

 

 

Financial liabilities - borrowings

 

119,430

 

143,109

 

134,435

 

Trade and other payables

 

473,867

 

786,191

 

767,163

 

Provisions

 

33,162

 

15,050

 

-

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Total current liabilities

 

626,459

 

944,350

 

901,598

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Net current assets

 

5,888,140

 

5,022,499

 

5,040,607

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Non-current liabilities

 

 

 

 

 

 

 

Financial liabilities - borrowings

 

170,232

 

219,445

 

263,664

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Net assets

 

6,408,066

 

5,546,043

 

6,156,100

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

EQUITY

 

 

 

 

 

 

 

Ordinary shares

 

13,252,298

 

12,463,836

 

12,178,122

 

Share premium

 

18,728,519

 

15,678,054

 

15,148,894

 

Merger reserve

 

106,148

 

106,148

 

106,148

 

Other reserves

 

(3,316,753)

 

(3,373,745)

 

(3,531,612)

 

Retained earnings

 

(22,362,146)

 

(19,328,250)

 

(17,745,452)

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Total equity

 

6,408,066

 

5,546,043

 

6,156,100

 

 

 

 

 

 

 

 

 

 


ImmuPharma plc

CONSOLIDATED STATEMENT OF CHANGES IN EQUITY

FOR THE PERIOD ENDED 30 JUNE 2017

 


Share capital


Share premium


 

Merger

reserve


Other reserves -

Acquisition

reserve


Other reserves -

Translation

Reserve


Other reserves -

Equity shares

to be issued

 

 

 

Retained

Earnings


Total

equity

 


£


£


£


£


£


£


£


£

 

At 1 January 2016

 

8,862,246


10,490,920


106,148


(3,541,203)


(1,926,850)


1,703,380


(14,004,234)


1,690,407

 

Loss for the financial period

-


-


-


-


-


-


(3,741,218)


(3,741,218)

 

Exchange differences on translation

of foreign operations

-


-


-


-


224,692


-


-


224,692

 

New issue of equity capital

3,315,876


5,305,401


-


-


-


-


-


8,621,277

 

Cost of new issue of equity capital

-


(647,427)


-


-


-


-


-


(647,427)

 

Share based payments

-


-


-


-


-


8,369


-


8,369

 

















 

At 30 June 2016

12,178,122


15,148,894


106,148


(3,541,203)


(1,702,158)


1,711,749


(17,745,452)


6,156,100

 

















 

At 1 January 2016

8,862,246


10,490,920


106,148


(3,541,203)


(1,926,850)


1,703,380


(14,004,234)


1,690,407

 

















 

Loss for the financial year

-


-


-


-


                   -


-


(5,324,016)


(5,324,016)

 

Exchange differences on translation

of foreign operations

-


-


-


-


                         317,177


-


-


317,177

 

New issue of equity capital

3,601,590


5,798,410


-


-


-


-


-


9,400,000

 

Cost of new issue of equity capital

-


(611,276)


-


-


-


-


-


(611,276)

 

Share based payment

-


-


-


-


-


73,751


-


73,751

 

















 

At 31 December 2016 & 1 January 2017

12,463,836


15,678,054


106,148


(3,541,203)


(1,609,673)


1,777,131


(19,328,250)


5,546,043

 

















 

Loss for the financial period

-


-


-


-


-


-


(3,033,896)


(3,033,896)

 

Exchange differences on translation

of foreign operations

-


-


-


-


(56,133)


-


-


(56,133)

 

New issue of equity capital

788,462


3,311,542


-


-


-


-


-


4,100,004

 

Cost of new issue of equity capital

-


(261,077)


-


-


-


-


-


(261,077)

 

Share based payment

-


-


-


-


-


113,125


-


113,125

 

















 

At 30 June 2017

13,252,298


18,728,519


106,148


(3,541,203)


(1,665,806)


1,890,256


(22,362,146)


6,408,066

 

Attributable to:-
















 

















 

Equity holders of the parent company

13,252,298


18,728,519


106,148


(3,541,203)


(1,665,806)


1,890,256


(22,362,146)


6,408,066

 


















ImmuPharma plc

 

CONSOLIDATED STATEMENT OF CASHFLOWS

FOR THE PERIOD ENDED 30 JUNE 2017

 

 

Note

Unaudited

6 months ended

30 June 2017

 

Audited

Year

 ended

31 December

2016

 

Unaudited

6 months ended

30 June

2016

(Restated)

 

 

 

£

 

£

 

£

 

Cash flows from operating activities

 

 

 

 

 

 

 

Cash used in operations

3

(3,200,329)

 

(7,191,318)

 

(4,484,973)

 

Tax

 

6,680

 

707,135

 

5,944

 

Interest paid

 

(375)

 

(1,917)

 

(496)

 

 

 

 

 

 

 

 

 

 

Net cash used in operating activities

 

(3,194,024)

 

 

(6,486,100)

 

(4,479,525)

 

 

 

 

 

 

 

 

 

 

 


 

 

 


 

Investing activities

 

 

 

 

 

 

 

Purchase of property, plant and equipment

 

(1,595)

 

(4,731)

 

(3,404)

 

Interest received

 

170

 

1,722

 

362

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Net cash used in investing activities

 

(1,425)

 

(3,009)

 

(3,042)

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Financing activities

 

 

 

 

 

 

 

(Decrease) in bank overdraft

 

             (138)

 

(1,091)

 

(1,199)

 

Loan repayments

 

(80,447)

 

(143,482)

 

(93,579)

 

Gross proceeds from issue of new share capital

 

4,100,004

 

9,400,000

 

8,621,277

 

Settlements from sharing agreement                

 4

682,360

 

2,690,451

 

309,650

 

Share capital issue costs

 

(261,077)

 

(611,276)

 

(647,427)

 

Funds deferred per sharing agreement             

 4

-

 

(3,949,230)

 

(3,949,230)

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Net cash generated from /(used in) financing activities

 

4,440,702

 

7,385,372

 

4,239,492

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Net  increase/(decrease) in cash and cash equivalents

 

 

1,245,253

 

896,263

 

(243,075)

 

Cash and cash equivalents at start of period

 

1,876,718

 

833,388

 

833,388

 

 

Effects of exchange rates on cash and

cash equivalents

 

9,624

 

 

(147,067)

 

 

70,696

 

 

 

 

 

 

 

 

 

 

 

Cash and cash equivalents at end of period

 

 

3,131,595

 

1,876,718

 

 

661,009

 

 

 

 

 

 

 

 

 

 

 


ImmuPharma plc

 

NOTES TO THE CONSOLIDATED INTERIM ACCOUNTS FOR THE PERIOD ENDED 30 JUNE 2017

 

1          ACCOUNTING POLICIES

 

Basis of preparation

 

The interim financial information in this report has been prepared using accounting policies consistent with IFRS as adopted by the European Union. IFRS is subject to amendment and interpretation by the International Accounting Standards Board (IASB) and the IFRS Interpretations Committee and there is an ongoing process of review and endorsement by the European Commission.  The financial information has been prepared on the basis of IFRS to be adopted by the European Union and applicable as at 31 December 2017. The Group has chosen not to adopt IAS 34 "Interim Financial Statements" in preparing the interim financial information.

 

            The accounting policies applied are consistent with those that were applied to the financial statements for the year ending 31 December 2016.

 

             Non-Statutory accounts

 

The financial information set out in this interim report does not constitute the Group's statutory accounts, within the meaning of Section 434 of the Companies Act 2006. The statutory accounts for the year ended 31 December 2016 have been filed with Registrar of Companies. The auditors reported on those accounts; their report was unqualified, did not contain a statement under either Section 498 (2) or Section 498 (3) of the Companies Act 2006 and did not include references to any matters to which the auditor drew attention by way of emphasis.  The financial information for the 6 months ended 30 June 2017 and 30 June 2016 is unaudited.

 

             Copies of this statement will be available on the Company's website - www.immupharma.com.

 

 

 

 

 

            

 

 

 

 

 



 

ImmuPharma plc

 

NOTES TO THE CONSOLIDATED INTERIM ACCOUNTS FOR THE PERIOD ENDED 30 JUNE 2017

(Continued)

 

 

2              LOSS PER SHARE

               

 

 

Unaudited
6 months ended 30 June 2017

 

Audited

Year ended 31 December

2016

 

Unaudited
6 months ended 30 June 2016

 

£

 

£

 

£

 

 

 

 

 

 

Loss

 

 

 

 

 

Loss for the purposes of basic and diluted loss per share being net loss attributable to equity shareholders

(3,033,896)

 



(5,324,016)

 

(3,741,218)

 

 

 

 

 

 

 


 

 

 


Number of shares

 

 

 

 

 

Weighted average number of ordinary shares for the purposes of basic loss per share

129,517,245

 

117,340,467

 

111,578,525

 

 

 

 

 

 

 

 

 

 

 

 

 

Basic loss per share

(2.34)p

 

(4.54)p

 

(3.35)p

 

 

 

 

 

 

 


 

 

 


 

 

 

 

 

 

Diluted loss per share

(2.34)p

 

(4.54)p

 

(3.35)p

 

 

 

 

 

 

 

 

 

 

 

 

 

There is no difference between basic loss per share and diluted loss per share as the share options and warrants are anti-dilutive.

 

The group has granted share options in respect of shares to be issued.

 

 

         

ImmuPharma plc

 

NOTES TO THE CONSOLIDATED INTERIM ACCOUNTS FOR THE PERIOD ENDED 30 JUNE 2017

(Continued)

 

3

CASH USED IN OPERATIONS

 

 

 

 

Unaudited

6 months ended

30 June 2017

 

Audited

Year ended 31 December 2016

 

Unaudited

6 months

ended

30 June 2016

 

 

 

 

£

 

£

 

£

 

 

 

 

 

 

 

 

 

 

 

Operating loss

 

(3,186,951)

 

(6,589,161)

 

(3,239,547)

 

 

Depreciation & amortisation

61,954

 

121,337

 

59,058

 

 

Share based payments

113,125

 

73,751

 

8,369

 

 

(Increase)/decrease in trade & other receivables

 

34,004

 

(387,713)

 

(915,358)

 

 

(Decrease) in trade & other payables

 

(322,963)

 

(403,414)

 

(392,281)

 

 

Increase in provisions

 

18,112

 

15,050

 

-

 

 

Gain/(loss) on foreign exchange

 

82,390

 

(21,168)

 

(5,214)

 

 

 

 

 

 

 

 

 

 

 

 

Cash used in operations

 

 

(3,200,329)

 

 

(7,191,318)

 

 

(4,484,973)

 

 

 

 

 

 

 

 

 

 

 

4

 

 

 

DERIVATIVE FINANCIAL ASSET

 

In February 2016, as part of a placing that raised, in aggregate, £8.4 million (before expenses) from new and existing shareholders, the Company issued 17,021,277 new ordinary shares to Lanstead Capital LP at a price of 26p per share for £4.4 million. All of the shares were allotted to Lanstead with full voting rights at that date. The Company simultaneously entered into a sharing agreement with Lanstead with a reference price of 34.6667p per share. The sharing agreement is for an 18 month period. The actual consideration is variable depending upon the Company's share price. The agreement is treated as a derivative financial asset and valued at fair value through the income statement with reference to the Company's share price.

 

Of the subscription proceeds of £4.4 million received from Lanstead, £3.76 million (85%) was invested by the Company in the sharing agreement and will be received in monthly instalments over the life of the agreement.  The remaining £663,820 (15%) was available for immediate working capital purposes.

 

The Company also issued, in aggregate, a further 851,064 new ordinary shares to Lanstead as a value payment in connection with the agreement.

 

At the end of the accounting period the amount receivable is restated to fair value based upon the share price of the Company at that date. Any change in the fair value of the derivative financial asset is reflected in the income statement.

 

5

SUBSEQUENT EVENTS

 

 

 

 

There were no events subsequent to 30 June 2017.

 

 

 

 

 

 

 

 


This information is provided by RNS
The company news service from the London Stock Exchange
 
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