Annual Information Update

Intl. Biotechnology Trust PLC
26 November 2007


                                                                26 November 2007

                           Annual Information Update


As required by Prospectus Rule 5.2, International Biotechnology Trust plc, (the
'Company') notifies all information which has been made available to the public
by the Company in the United Kingdom (being the Company's Home State) in the
last 12 months that is required to be disclosed pursuant to this Rule.

In order to avoid an unnecessarily lengthy document, information is referred to
in this update rather than included in full.  The information referred to in
this update was up to date at the time the information was published but some
information may now be out of date.

Announcements made via RNS, a Regulatory Information Service

The announcements in the table below were published via RNS on the dates
indicated.


Date announced                          Brief description of document

04 December 2006                        Portfolio Update

07 December 2006                        Net Asset Value(s)

12 December 2006                        Net Asset Value(s)

14 December 2006                        Net Asset Value(s)

18 December 2006                        Net Asset Value(s)

19 December 2006                        Net Asset Value(s)

21 December 2006                        Net Asset Value(s)

22 December 2006                        Total Voting Rights

04 January 2007                         Net Asset Value(s)

05 January 2007                         Net Asset Value(s)

08 January 2007                         Net Asset Value(s)

12 January 2007                         Issue of Equity

15 January 2007                         Net Asset Value(s)

16 January 2007                         Net Asset Value(s)

17 January 2007                         Net Asset Value(s)

18 January 2007                         Net Asset Value(s)

23 January 2007                         Net Asset Value(s)

24 January 2007                         Net Asset Value(s)

25 January 2007                         Net Asset Value(s)

30 January 2007                         Net Asset Value(s)

30 January 2007                         Net Asset Value(s)

02 February 2007                        Net Asset Value(s)

05 February 2007                        Net Asset Value(s)

07 February 2007                        Net Asset Value(s)

07 February 2007                        EGM Result & C Share Issue

08 February 2007                        Net Asset Value(s)

09 February 2007                        Holding(s) in Company

09 February 2007                        Holding(s) in Company

12 February 2007                        Net Asset Value(s)

13 February 2007                        Net Asset Value(s)

14 February 2007                        Total Voting Rights

14 February 2007                        Director/PDMR Shareholding

14 February 2007                        Director/PDMR Shareholding

19 February 2007                        Net Asset Value(s)

21 February 2007                        Net Asset Value(s)

22 February 2007                        Net Asset Value(s)

23 February 2007                        Net Asset Value(s)

27 February 2007                        Net Asset Value(s)

28 February 2007                        Net Asset Value(s)

28 February 2007                        Total Voting Rights

05 March 2007                           Net Asset Value(s)

07 March 2007                           Net Asset Value(s)-Amendment

07 March 2007                           Portfolio Update

07 March 2007                           Net Asset Value(s)

08 March 2007                           Net Asset Value(s)

13 March 2007                           Net Asset Value(s)

13 March 2007                           Net Asset Value(s)

15 March 2007                           Net Asset Value(s)

19 March 2007                           Portfolio Update

19 March 2007                           Net Asset Value(s)

20 March 2007                           Net Asset Value(s)

26 March 2007                           Net Asset Value(s) - Replace

26 March 2007                           Net Asset Value(s)

28 March 2007                           Portfolio Update

28 March 2007                           Net Asset Value(s)

30 March 2007                           Net Asset Value(s)

03 April 2007                           Net Asset Value(s)

04 April 2007                           Net Asset Value(s)

05 April 2007                           Net Asset Value(s)

12 April 2007                           Interim Results

13 April 2007                           Net Asset Value(s)

16 April 2007                           Net Asset Value(s)

16 April 2007                           Net Asset Value(s)

17 April 2007                           Net Asset Value(s)

18 April 2007                           Net Asset Value(s)

19 April 2007                           Net Asset Value(s)

20 April 2007                           Net Asset Value(s)

23 April 2007                           Net Asset Value(s)

24 April 2007                           Net Asset Value(s)

25 April 2007                           Net Asset Value(s)

26 April 2007                           Net Asset Value(s)

27 April 2007                           Net Asset Value(s)

30 April 2007                           Net Asset Value(s)

01 May 2007                             Net Asset Value(s)

02 May 2007                             Net Asset Value(s)

03 May 2007                             Net Asset Value(s)

04 May 2007                             Net Asset Value(s)

08 May 2007                             Net Asset Value(s)

09 May 2007                             C Share Conversion

09 May 2007                             Net Asset Value(s)

10 May 2007                             Net Asset Value(s)

11 May 2007                             Net Asset Value(s)

14 May 2007                             Net Asset Value(s)

15 May 2007                             Net Asset Value(s)

16 May 2007                             Net Asset Value(s)

17 May 2007                             Conversion of Securities

17 May 2007                             Net Asset Value(s)

18 May 2007                             Net Asset Value(s)

21 May 2007                             Net Asset Value(s)

22 May 2007                             Ordinary Shares Listing Date

22 May 2007                             Net Asset Value(s)

23 May 2007                             Net Asset Value(s)

24 May 2007                             Net Asset Value(s)

25 May 2007                             Net Asset Value(s)

29 May 2007                             Net Asset Value(s)

30 May 2007                             Net Asset Value(s)

31 May 2007                             Net Asset Value(s)

31 May 2007                             Total Voting Rights

01 June 2007                            Net Asset Value(s)

04 June 2007                            Net Asset Value(s)

04 June 2007                            Portfolio Update

05 June 2007                            Net Asset Value(s)

06 June 2007                            Net Asset Value(s)

07 June 2007                            Net Asset Value(s)

07 June 2007                            Director/PDMR Shareholding

07 June 2007                            Director/PDMR Shareholding

08 June 2007                            Net Asset Value(s)

11 June 2007                            Portfolio Company/NAV

12 June 2007                            Net Asset Value(s)

12 June 2007                            Interim Report

13 June 2007                            Net Asset Value(s)

14 June 2007                            Net Asset Value(s)

15 June 2007                            Net Asset Value(s)

18 June 2007                            Net Asset Value(s)

20 June 2007                            Net Asset Value(s)

20 June 2007                            Net Asset Value(s)

21 June 2007                            Net Asset Value(s)

22 June 2007                            Net Asset Value(s)

25 June 2007                            Net Asset Value(s)

26 June 2007                            Net Asset Value(s)

27 June 2007                            Net Asset Value(s)

28 June 2007                            Net Asset Value(s)

28 June 2007                            Director Declaration

29 June 2007                            Net Asset Value(s)

02 July 2007                            Net Asset Value(s)

03 July 2007                            Net Asset Value(s)

04 July 2007                            Net Asset Value(s)

05 July 2007                            Net Asset Value(s)

06 July 2007                            Net Asset Value(s)

09 July 2007                            Blocklisting Application

09 July 2007                            Net Asset Value(s)

10 July 2007                            Net Asset Value(s)

11 July 2007                            Net Asset Value(s)

12 July 2007                            Net Asset Value(s)

13 July 2007                            Net Asset Value(s)

16 July 2007                            Net Asset Value(s)

17 July 2007                            Net Asset Value(s)

18 July 2007                            Net Asset Value(s)

19 July 2007                            Net Asset Value(s)

20 July 2007                            Net Asset Value(s)

23 July 2007                            Net Asset Value(s)

24 July 2007                            Net Asset Value(s)

25 July 2007                            Net Asset Value(s)

26 July 2007                            Net Asset Value(s)

27 July 2007                            Net Asset Value(s)

30 July 2007                            Net Asset Value(s)

31 July 2007                            Net Asset Value(s)

31 July 2007                            Total Voting Rights

01 August 2007                          Net Asset Value(s)

02 August 2007                          Net Asset Value(s)

03 August 2007                          Net Asset Value(s)

03 August 2007                          Holding(s) in Company

06 August 2007                          Net Asset Value(s)

07 August 2007                          Net Asset Value(s)

08 August 2007                          Holding(s) in Company

08 August 2007                          Net Asset Value(s)

09 August 2007                          Net Asset Value(s)

10 August 2007                          Net Asset Value(s)

13 August 2007                          Net Asset Value(s)

14 August 2007                          Net Asset Value(s)

15 August 2007                          Net Asset Value(s)

16 August 2007                          Net Asset Value(s)

17 August 2007                          Net Asset Value(s)

20 August 2007                          Net Asset Value(s)

21 August 2007                          Net Asset Value(s)

22 August 2007                          Net Asset Value(s)

23 August 2007                          Net Asset Value(s)

28 August 2007                          Net Asset Value(s)

28 August 2007                          Net Asset Value(s)

29 August 2007                          Net Asset Value(s)

31 August 2007                          Net Asset Value(s)

31 August 2007                          Net Asset Value(s)

04 September 2007                       Net Asset Value(s)

05 September 2007                       Portfolio Update

05 September 2007                       Net Asset Value(s)

05 September 2007                       Portfolio Update

06 September 2007                       Net Asset Value(s)

07 September 2007                       Net Asset Value(s)

07 September 2007                       Net Asset Value(s)

10 September 2007                       Net Asset Value(s)

11 September 2007                       Net Asset Value(s)

12 September 2007                       Net Asset Value(s)

13 September 2007                       Net Asset Value(s)

14 September 2007                       Net Asset Value(s)

17 September 2007                       Net Asset Value(s)

18 September 2007                       Net Asset Value(s)

19 September 2007                       Net Asset Value(s)

20 September 2007                       Net Asset Value(s)

21 September 2007                       Net Asset Value(s)

24 September 2007                       Net Asset Value(s)

25 September 2007                       Net Asset Value(s)

26 September 2007                       Net Asset Value(s)

27 September 2007                       Net Asset Value(s)

28 September 2007                       Net Asset Value(s)

01 October 2007                         Net Asset Value(s)

02 October 2007                         Net Asset Value(s)

03 October 2007                         Net Asset Value(s)

04 October 2007                         Net Asset Value(s)

05 October 2007                         Net Asset Value(s)

08 October 2007                         Net Asset Value(s)

09 October 2007                         Net Asset Value(s)

10 October 2007                         Net Asset Value(s)

12 October 2007                         Net Asset Value(s) - Amendment

12 October 2007                         Net Asset Value(s)

15 October 2007                         Net Asset Value(s)

16 October 2007                         Net Asset Value(s)

17 October 2007                         Net Asset Value(s)

18 October 2007                         Final Results - Announcement

18 October 2007                         Net Asset Value(s)

18 October 2007                         Portfolio Update

19 October 2007                         Net Asset Value(s)

22 October 2007                         Net Asset Value(s)

23 October 2007                         Net Asset Value(s)

24 October 2007                         Net Asset Value(s)

25 October 2007                         Net Asset Value(s)

26 October 2007                         Net Asset Value(s)

29 October 2007                         Net Asset Value(s)

30 October 2007                         Net Asset Value(s)

31 October 2007                         Net Asset Value(s)

01 November 2007                        Net Asset Value(s)

02 November 2007                        Net Asset Value(s)

05 November 2007                        Net Asset Value(s)

06 November 2007                        Net Asset Value(s)

07 November 2007                        Net Asset Value(s)

08 November 2007                        Net Asset Value(s)

09 November 2007                        Annual Report and Accounts

12 November 2007                        Net Asset Value(s)

13 November 2007                        Net Asset Value(s)

14 November 2007                        Net Asset Value(s)

15 November 2007                        Net Asset Value(s)

16 November 2007                        Net Asset Value(s)

19 November 2007                        Net Asset Value(s)

20 November 2007                        Net Asset Value(s)

21 November 2007                        Net Asset Value(s)

23 November 2007                        Net Asset Value(s)

Copies of the document and published via RNS can be obtained from the London
Stock Exchange website, or the Company's Registered Office at 31 Gresham Street,
London EC2V 7QA.

Documents filed at Companies House

All of the documents listed below were filed with Companies House in Cardiff on
or around the dates indicated.


Date of Filing                        Brief description of document(s) filed

07 January 2007                       Annual Report and Accounts

26 February 2007                      Resolution -Authorise Allotment of Security

27 February 2007                      Resolution -Authorise Allotment of Security

27 February 2007                      Articles of Association

16 March 2007                         Annual Return

07 July 2007                          Declaration of mortgage/charge

26 July 2007                          Auditors' Resignation


Copies of the documents filed at Companies House can be obtained from Companies
House or from the Company Secretary at the Company's Registered Office at 31
Gresham Street, London EC2V 7QA.

_____________________________________________________________________



Enquiries:

Louise Richard
Schroder Investment Management Limited                      020 7658 6501


                      This information is provided by RNS
            The company news service from the London Stock Exchange      IUQQLFLDFBFFBQ