Blocklisting

Intl. Biotechnology Trust PLC
11 January 2008



                                                                 11 January 2008




                      BLOCK LISTING SIX-MONTHLY RETURN 



1.      Name of Company: INTERNATIONAL BIOTECHNOLOGY TRUST PLC



2.      Name of scheme: GENERAL CORPORATE PURPOSES SCHEME



3.      Period of return: FROM 9 JULY 2007 TO 9 JANUARY 2008



4.      Number and class of share(s) not issued under scheme: 

        791,067 ORDINARY SHARES



5.      Number of shares issued/allotted under scheme during the period: 950,000



6.      Balance under scheme not yet issued/allotted at end of period: 
  
        791,067 ORDINARY SHARES



 7. Number and class of shares(s) (amount of stock/debt securities) originally
    listed and the date of admission: 1,741,067 - ADMITTED TO LISTING ON 
    9 JULY 2007



Please confirm the total number of shares in issue at the end of the period in
order for us to update our records: 70,592,664 ORDINARY SHARES OF 25 PENCE EACH



Enquiries:



Louise Richard

Schroder Investment Management Limited
Tel: [phone]




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