Director Shareholding

Intl. Biotechnology Trust PLC 28 February 2005 SCHEDULE 11 NOTIFICATION OF INTERESTS OF DIRECTORS AND CONNECTED PERSONS 1. Name of company International Biotechnology Trust plc 2. Name of director Mr Andrew Barker 3. Please state whether notification indicates that it is in respect of holding of the shareholder named in 2 above or in respect of a non-beneficial interest or in the case of an individual holder if it is a holding of that person's spouse or children under the age of 18 or in respect of a non-beneficial interest Director only 4. Name of the registered holder(s) and, if more than one holder, the number of shares held by each of them (if notified) Rock Nominees Limited 5. Please state whether notification relates to a person(s) connected with the director named in 2 above and identify the connected person(s) N/A 6. Please state the nature of the transaction. For PEP transactions please indicate whether general/single co PEP and if discretionary/non discretionary Market Purchase of shares 7. Number of shares / amount of stock acquired 10,000 8. Percentage of issued class 0.0208% 9. Number of shares/amount of stock disposed - 10. Percentage of issued class - 11. Class of security Ordinary shares 12. Price per share 105.5p 13. Date of transaction 28 February 2005 14. Date company informed 28 February 2005 15. Total holding following this notification 125,000 ordinary shares 16. Total percentage holding of issued class following this notification 0.2614% If a director has been granted options by the company please complete the following boxes. 17. Date of grant 18. Period during which or date on which exercisable 19. Total amount paid (if any) for grant of the option 20. Description of shares or debentures involved: class, number 21. Exercise price (if fixed at time of grant) or indication that price is to be fixed at time of exercise 22. Total number of shares or debentures over which options held following this notification 23. Any additional information 24. Name of contact and telephone number for queries John Spedding - 020 7658 3206 25. Name and signature of authorised company official responsible for making this notification John Spedding Date of Notification 28 February 2005 The FSA does not give any express or implied warranty as to the accuracy of this document or material and does not accept any liability for error or omission. The FSA is not liable for any damages (including, without limitation, damages for loss of business or loss of profits) arising in contract, tort or otherwise from the use of or inability to use this document, or any material contained in it, or from any action or decision taken as a result of using this document or any such material. This information is provided by RNS The company news service from the London Stock Exchange
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