Directorate Change

Intl. Biotechnology Trust PLC
02 March 2004




                                                                    2 March 2004

                            Appointment of Director


International Biotechnology Trust plc is pleased to announce that Dr David
Clough has been appointed as a Director of the Company.

Dr Clough, aged 57, was Director of Research at Roche in the UK between 1986 and
1999. He was responsible for over 300 staff with departments covering chemistry,
biology and pre-clinical development. During this time, 2 products discovered by
staff in the research group under Dr Clough progressed to the market place,
namely Inhibace and Invirase. Dr Clough has received several national and
international awards for his role in the discovery of Invirase, including the UK
and International Prix Galien, The PhRMA Discoverers Award and the UK Millennium
Product Award.

Dr Clough is currently on the Board of Fulcrum Pharma PLC and on the Scientific
Advisory Boards of Cambridge Antibody Technology, Anadys and Kinetique.

Dr Clough holds a PhD from Glasgow University.

It is confirmed that there are no details to be disclosed concerning Dr Clough
under paragraph 6.F.2(b) to (g) of the UK Listing Rules.




Enquiries:

John Spedding

Schroder Investment Management Limited           Tel: [phone]


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