Holding in Company

Intl. Biotechnology Trust PLC
23 August 2000


Schedule 10 - Notification of Major Interests in Shares

1   Name of company:
Int'l Biotechnology Trust Plc

2   Name of shareholder having a major interest:
Millennium Partners L.P.

3   Please state whether notification indicates that it is in respect of
holding of the shareholder named in 2 above or in respect of a non-beneficial
interest or in the case of an individual holder if it is a holding of that
person's spouse or children under the age of 18:
As in 2 above

4   Name of registered holder(s) and, if more than one holder, the number of
shares held by each of them:
Millennium Partners L.P.    8,850,000
Vidacos Nominees Ltd        1,020,000

5   Number of shares/amount of stock acquired:
N/A

6   Percentage of issued class:
N/A

7   Number of shares/amount of stock disposed:
N/A

8   Percentage of issued class:
N/A

9   Class of security:
Ordinary Shares of 25p each

10  Date of transaction:
N/A

11  Date company informed:
22nd August 2000

12  Total holding following this notification:
9,870,000

13  Total percentage holding of issued class following this notification:
11.22%

14  Contact name for queries:
Tom Stevenson

15 Contact telephone number:
020 7517 6432

16  Name of company official responsible for making notification:
Tom Stevenson

17  Date of notification:
23rd August 2000



Additional Information: