Holding(s) in Company

Intl. Biotechnology Trust PLC
04 June 2003


                                                                     4 June 2003


                    Substantial Share Interest Notification


We are writing to advise that the Company was notified on 4 June 2003 that,
following a sale of 570,000 ordinary shares on 3 June 2003, East Riding of
Yorkshire Council no longer has a notifiable interest in the Company's issued
share capital.



Enquiries:

John Spedding
Schroder Investment Management Limited          Tel: [phone]


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