Holding(s) in Company

Intl. Biotechnology Trust PLC
10 November 2005


                                                                10 November 2005

                    Substantial Share Interest Notification


The Company was notified on 10 November 2005 that, Deutsche Bank AG no longer
holds a notifiable interest in the 25p ordinary shares of the Company.

The transaction details and date were not disclosed.


Enquiries:

John Spedding
Schroder Investment Management Limited                  Tel: [phone]




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