Portfolio Update

Intl. Biotechnology Trust PLC 03 June 2004 FOR IMMEDIATE RELEASE 03-June-04 To : The London Stock Exchange International Biotechnology Trust plc The Board of International Biotechnology Trust plc announces that the top ten investments as at Monday 31 May 2004 were as follows: NAME % of Gross Assets Top 10 Investments Eyetech Pharmaceuticals 16.34 OSI Pharmaceuticals 7.53 Encysive Pharmaceuticals 4.98 Affibody 4.36 Sunesis Pharmaceuticals 4.06 Aderis Pharmaceuticals 4.06 AnorMed 3.51 Nektar Therapeutics 3.49 Inflazyme Pharmaceuticals 3.00 Atrix Laboratories 2.64 By Order of the Board Schroder Investment Management Limited Secretaries Enquiries : International Biotechnology Trust plc Anthony Carney 020 7658 2548 This information is provided by RNS The company news service from the London Stock Exchange
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