Portfolio Update

Intl. Biotechnology Trust PLC
04 December 2007





                     International Biotechnology Trust plc


The Board of International Biotechnology Trust plc announces that the top ten
holdings as a percentage of net assets at Friday 30 November 2007 are:

Gyrus Group                                                              4.54
MGI Pharma Com                                                           4.48
Celgene Com                                                              4.43
CSL NPV                                                                  4.23
Insight Liquidity Funds                                                  4.02
Gilead Sciences Com                                                      3.93
Inverness Medical Innovation Com                                         3.14
Applera-Celara Genomics Group Com                                        3.06
Morphosys NPV                                                            3.05
OSI Pharmaceuticals Com                                                  3.03


                             By Order of the Board
                     Schroder Investment Management Limited
                               Company Secretary


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Enquiries :

International Biotechnology Trust plc
Tina Watts 020 7658 3581


                      This information is provided by RNS
            The company news service from the London Stock Exchange