Investment in Avacta Limited

IP2IPO Group PLC 11 August 2005 For immediate release 11 August 2005 IP2IPO Group Plc Investment in Avacta Limited IP2IPO Group Plc (AIM: IPO) ('IP2IPO') is pleased to announce that it has invested £300,000 in cash in Avacta Limited ('Avacta'), a spin-out company from the University of Leeds. IP2IPO's investment into Avacta increases its equity interest to a 46.8% stake. Avacta is developing breakthrough technology that integrates multiple spectroscopic techniques with novel biotechnology to enable the unique characterization of highly complex biological and chemical substances - even at the level of single molecule sensitivity. This technology platform has a number of different applications in the homeland security, healthcare, biotechnology and pharmaceutical sectors. The company is already working on a major collaborative project developing technology for remote detection of hazardous substances for defence and counter terrorism purposes. Avacta has also developed technology to enable high throughput screening of membrane bound drug targets which represent approximately 35% of predicted new targets. Due to their insolubility, membrane proteins are particularly difficult to handle and no high throughput screening technique is currently available to the pharmaceutical industry. Avacta is headed by Professor Alastair Smith, Professor of Molecular Biophysics at the University of Leeds, who has a world class track record of developing enabling technologies for the biophysical sciences. Avacta's co-founders are Dr Simon Webster, Dr Kurt Baldwin and Alan Brain. Drs Webster and Baldwin previously worked with Renishaw plc and were key members of the team that was responsible for designing the world's market leading Raman spectrometers. Mr Brain was formerly the Head of Microscopy at Smith and Nephew Research Centre in York. Professor Smith, Chief Executive of Avacta, said: 'We have developed Avacta's IP in response to significant unmet market needs. We believe that the ability of our platform technologies to uniquely characterize complex chemical and biological systems will lead to a range of products that will provide enormous benefits to companies operating in the healthcare, homeland security, biotechnology and pharmaceutical sectors. This investment will enable us to complete the development of our first products.' For more information please contact: IP2IPO 020 7489 5200 David Norwood, Chief Executive Officer Avacta, University of Leeds 0113 343 3875 Prof. A. Smith, Chief Executive Officer Buchanan Communications 020 7466 5000 Mark Court, Mary-Jane Johnson Notes for editors IP2IPO is an intellectual property (IP) company that specialises in commercialising university technology. The Company was founded in 2001 and listed on the AIM Market of the London Stock Exchange plc in October 2003. IP2IPO's first partnership was with the University of Oxford. In return for an investment of £20 million, IP2IPO has acquired 50 per cent of the University of Oxford's equity in spin-out companies and technology licenses based on intellectual property created at the Chemistry Department until 2015. In November 2003, IP2IPO created a £5 million seed capital fund for investing in spin-out companies across the University of Oxford, not just those originating within the Chemistry Department. In March 2002, IP2IPO entered into a second long-term partnership with the University of Southampton. Under the terms of this partnership, IP2IPO is committed to working with the University of Southampton in the identification and facilitation of spin-out companies from across the University of Southampton and to investing £5 million in early-stage University of Southampton spin-out companies over a four year period in return for equity stakes in those companies. In addition, IP2IPO also received a 20 per cent stake in Southampton Asset Management Limited, a company that has been formed to hold the University's equity stakes in its spin-out companies. The partnership has a term of at least 25 years. IP2IPO entered into its third long-term partnership in May 2003 with King's College London. IP2IPO will work with King's College London to help identify and progress commercialisation opportunities as well as invest £5 million in seed capital in spin-out companies from King's College London over a five year period in return for equity stakes in those companies. In addition, IP2IPO will receive 20 per cent of King's College London's equity in spin-out companies and technology licenses. The partnership has a term of 25 years. In October 2003, IP2IPO announced a fourth partnership with the Centre for Novel Agricultural Products ('CNAP'), based at the University of York. CNAP is a flagship research centre that specialises in plant and microbial gene discovery. Under the terms of the partnership a new company, Amaethon Limited, has been created which has the right to commercialise CNAP's IP for 25 years. IP2IPO has invested £1.15m in Amaethon Limited in return for a 40% equity stake in Amaethon Limited (the remaining equity being owned by the University of York) and will also invest in the spin-out companies based on CNAP's IP which Amaethon Limited creates. In June 2004, IP2IPO acquired Top Technology Ventures Limited, an investment adviser to early stage technology funds. This combines IP2IPO's expertise in the creation of new ventures based on world leading university IP with Top Technology's focus on making early stage venture capital investments. In January 2005, IP2IPO acquired Techtran, a company set up in 2002 to commercialise university intellectual property under a long-term technology commercialisation contract with the University of Leeds. Under the terms of the contract Techtran receives a significant (30%) interest in spin-out companies created and technology licences negotiated, in return for the provision of technology transfer services to the University. In May 2005, IP2IPO announced the launch of LifeUK, a new subsidiary company. LifeUK will in-license life science intellectual property created by medical researchers at universities with which IP2IPO already has partnerships, other universities in the UK and similar academic and charitable research institutions. LifeUK's objective is to further develop the intellectual property which it in-licenses with a view to creating substantial value either by subsequently licensing these development programmes to the pharmaceutical industry or via the creation of new ventures. To date, 4 spin-out companies from the IP2IPO portfolio have listed on the AIM Market of the London Stock Exchange plc: Offshore Hydrocarbon Mapping plc, Synairgen plc, VASTox plc and Proximagen Neuroscience plc. This information is provided by RNS The company news service from the London Stock Exchange SCIFFFVTAIILIE

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