Re Agreement

IP2IPO Group PLC 10 November 2003 For Immediate Release 10 November 2003 IP2IPO Group plc IP2IPO to invest directly in University of Oxford spin-out companies IP2IPO Group plc (AIM: IPO), the intellectual property business that commercialises university technology, is pleased to announce it has reserved £5 million for making seed capital investments in University of Oxford spin-out companies. IP2IPO, the University of Oxford and Isis Innovation Limited (the University's technology transfer company) have a long-standing relationship. In late 2000, the parties entered into a fifteen-year agreement under which IP2IPO acquired 50 per cent of the University's interest in spin-out companies based on intellectual property created at the University of Oxford's Chemistry Department. The partnership has proved extremely successful. Six spin-out companies have been created from the Chemistry Department during the past two years, including VASTox Limited, a chemical genomics company (formed by Professor Steve Davies, the founder of Oxford Asymmetry International plc) and Glycoform Limited, an advanced drug delivery company based on carbohydrate chemistry. IP2IPO will use the £5 million seed capital fund to invest in spin-out opportunities from across the University of Oxford, not just those originating within the Chemistry Department. Commenting on today's announcement, Tom Hockaday, Executive Director of Isis, said: 'We are encouraged that IP2IPO is reserving £5m for investments in Oxford spin-out companies, which is a testament to the strength of research being carried out at the University of Oxford. We have a strong relationship with the team at IP2IPO and always welcome the arrival of new sources of investment finance. We have benefited from their involvement in chemistry projects and now look forward to working on a wider range of technology commercialisation opportunities.' David Norwood, IP2IPO's Chief Executive, said: 'In IP2IPO's experience, investing small amounts of seed capital in a disciplined way is a great means of enabling the formation of high quality spin-out companies. The Isis and IP2IPO teams have developed effective ways of creating spin-out companies from Oxford's Chemistry Department and this latest initiative is an opportunity to apply our joint approach to the University as a whole.' For more information contact: IP2IPO (www.ip2ipo.com) David Norwood, Chief Executive Officer 020 7071 4348 Buchanan Communications Tim Anderson, Mark Court, Mary-Jane Johnson 020 7466 5000 Notes to editors IP2IPO IP2IPO is an intellectual property (IP) company that specialises in commercialising university technology. The Company has already formed four long-term partnerships with UK universities and listed on AIM in October 2003. IP2IPO's first such collaboration was with the University of Oxford. In return for an investment of £20 million, IP2IPO has acquired 50 per cent of the University of Oxford's equity in spin-out companies and technology licences based on intellectual property created at the Chemistry Department until 2015. In March 2002, IP2IPO Limited entered into a second long-term partnership with the University of Southampton. Under the terms of this partnership, IP2IPO is committed to working with the University of Southampton in the identification and facilitation of spin-out companies from across the University of Southampton and to investing £5 million in early-stage University of Southampton spin-out companies over a four year period in return for equity stakes in those companies. In addition, IP2IPO Limited also received a 20 per cent stake in Southampton Asset Management Limited, a company that has been formed to hold the University's equity stakes in its future spin-out companies. The partnership has a term of at least 25 years. IP2IPO Limited entered into its third long-term partnership in May 2003 with King's College London. IP2IPO Limited will work with King's College London to help identify and progress commercialisation opportunities as well as invest £5 million in King's College London's spin-out companies over a five year period in return for equity stakes in those companies. In addition, IP2IPO Limited will receive 20 per cent. of King's College London's equity in spin-out companies and technology licenses. The partnership has an initial term of 25 years. In October 2003, IP2IPO announced a fourth partnership with the Centre for Novel Agricultural Products ('CNAP'), based at the University of York. CNAP is a flagship research centre that specialises in plant and microbial gene discovery. Under the terms of the partnership a new company, Amaethon Limited, has been created which has the right to commercialise CNAP's IP for 25 years. IP2IPO Limited has committed to invest £1.15m in Amaethon Limited in return for a one third equity stake in Amaethon Limited (the remaining equity being owned by the University of York) and will also invest in the spin out companies based on CNAP's IP which Amaethon Limited creates. Isis Innovation Isis Innovation Limited, the University of Oxford's wholly-owned technology transfer company established in 1988, is a world leader in university technology transfer. Isis currently files a patent a week and spins out a company every two months based on academic research generated within and owned by the University of Oxford. The combined value of the University of Oxford's companies has reached approximately £2 billion, using quoted market capitalisations and investor valuations for unquoted companies. The creation of these new spin-out companies benefits local economic development and has created many new jobs in the region. This information is provided by RNS The company news service from the London Stock Exchange

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