Annual Information Update

Phytopharm PLC 15 January 2007 Phytopharm plc Annual Information Update Phytopharm plc (the Company) announces that, in accordance with the requirements of Prospectus Rule 5.2 issued by the Financial Services Authority, and following publication of the Annual Report on 28 December 2006, the following information has been published or made available to the public during the 12 months ended 12 January 2007, in compliance with laws and rules dealing with the regulation of securities, issuers of securities and securities markets. For the purpose of this update, only references to the information are provided. Full copies of each item can be found at the locations specified below. In accordance with the provisions of Article 27.3 of the Prospectus Directive Regulations, we confirm that to the best of our knowledge, information relating to 'Holdings in Company' and 'Director/PDMR Shareholdings' is up to date at the date of this announcement, but it is acknowledged that such disclosures may, at any time, become out of date, due to changing circumstances. 1. Announcements made via Regulatory Information Services All documents listed below were published via a regulatory information service on the dates indicated: Date of publication Title 10 January 2007 Director/PDMR shareholding 10 January 2007 Director/PDMR shareholding 9 January 2007 Board changes 19 December 2006 Notification of total voting rights 10 November 2006 Director/PDMR shareholding 8 November 2006 Preliminary results for the year ended 31 August 2006 1 November 2006 Block listing interim review 27 October 2006 Notification of results 18 September 2006 Block listing interim review 5 September 2006 Board changes 21 July 2006 Board appointment 5 June 2006 Board appointment 19 May 2006 Holding(s) in company 11 May 2006 Director/PDMR shareholding 11 May 2006 Director/PDMR shareholding 8 May 2006 Interim results 3 May 2006 Block listing interim review 27 April 2006 Holding(s) in company 27 April 2006 Holding(s) in company 26 April 2006 Advisor appointment 24 April 2006 Product launch 10 April 2006 Research update 30 March 2006 Notice of results 17 March 2006 Block listing interim review 30 January 2006 Second price monitoring extension 30 January 2006 Price monitoring extension 24 January 2006 Results of AGM 2. Documents despatched to shareholders The following documents have been despatched by the Company to holders of its securities during the year: 27 December 2006 - Annual Report 2006 1 June 2006 - Interim Report 2006 3. Documents field at Companies House The Company has submitted the following Filings to Companies House: 11 January 2007 Form 288(a) Appointment of Director Mr Piers Morgan 11 January 2007 Form 288(b) Terminating appointment of Director - Dr Richard Dixey 5 December 2006 Form 363 Annual Return 6 September 2006 Form 288(b) Terminating appointment of Director - Dr Trevor Flanagan 6 September 2006 Form 288(b) Terminating appointment of Director - Mr Gordon Stevens 24 July 2006 Form 288(a) Appointment of Director - Dr Peter Blower 8 June 2006 Form 288(a) Appointment of Director - Mr Alexander Morrison 24 January 2006 Registration of special resolutions passed at AGM Copies of these documents can be obtained from Companies House, Crown Way, Cardiff CF14 3UZ (Telephone 0870 3333 636, email at enquiries@companies-house.gov.uk) or, if you are a registered user, through Companies House Direct at www.companies-house.gov.uk The Company's annual report and accounts 2006 (published on 28 December 2006) and Interim Report 2005 (published on 1 June 2006) can be found on the Company's website as can the Interim Results announcement for the six months ended 28 February 2006 (published on 8 May 2006) and the Preliminary Results Announcement (published on 8 November 2006), The Company's website is www.phytopharm.com. Copies of all documents referred to above are also available for inspection at the Company's registered office (Corpus Christi House, 9 West Street, Godmanchester, Cambs PE29 2HY, United Kingdom) during normal business hours or by request from the Company Secretary. For further information, please contact: Zoe McGowan, Company Secretary Phytopharm plc Tel No: +44 (0)1480 437697 Further information, about Phytopharm can be found on the Company's website www.phytopharm.com This information is provided by RNS The company news service from the London Stock Exchange

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