Appt: Broker & Joint Adviser

Phytopharm PLC 26 February 2003 26 February 2003 Phytopharm plc Appointment of Broker and Joint Financial Adviser Phytopharm plc, the UK-based, LSE listed botanical pharmaceuticals company, announces today the appointment of Nomura International plc as its broker and joint financial adviser, with immediate effect. -ENDS- Enquiries: Phytopharm plc Dr Richard Dixey, Chief Executive Tel: 01480 437697 Mobile: 07867 782000 Financial Dynamics David Yates / Tel: 0207 831 3113 Ben Atwell NOTES TO EDITORS Phytopharm plc Phytopharm is the leading company in the development of Botanical pharmaceuticals. Botanicals enable the rapid clinical evaluation of plant medicines in chronic and poorly understood diseases. Where novel modes of action are discovered, such research can form the basis for drug discovery platforms, which enable the development of new medicines and the isolation of single chemical entities of clinical importance. Phytopharm has four drug discovery platforms in full development, for metabolic syndrome, neurodegeneration, inflammation and dermatitis. Neurodegenerative disorders such as Parkinson's disease are chronic, progressive conditions that predominantly affect the middle aged and elderly, causing severe disability and premature death. In the US market alone, there are estimated to be one million patients with diagnosed Parkinson's disease and a further two million undiagnosed, with a cost to the economy of $10 billion in associated health care costs (source: AHP submission to US Congress). Despite substantial progress in our understanding of these conditions over recent years, in most cases the underlying cause(s) remain unknown. The currently available drug therapies can provide symptomatic improvement and in some cases may delay disease progression to a modest extent. The medical, social and economic impact of these diseases is increasing, particularly in the developed world, due to the ageing population. Phytopharm is developing nine products based on its four drug discovery platforms alongside a number of other projects in early evaluation phase. More information concerning Phytopharm's activities can be found on its web site at http://www.phytopharm.co.uk. This information is provided by RNS The company news service from the London Stock Exchange

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