Blocklisting Interim Review

Phytopharm PLC
03 May 2006



                      BLOCKLISTING SIX MONTHLY RETURN

INFORMATION PROVIDED ON THIS FORM MUST BE TYPED OR PRINTED ELECTRONICALLY.


To:  The FSA

Date:        


1. Name of applicant:      PHYTOPHARM PLC



2. Name of scheme          THE PHYTOPHARM 1996 COMPANY SHARE OPTION



3. Period of return:  From  1 NOVEMBER 2005    To  30 APRIL 2006 


4. Balance under scheme from previous return: 159,660 ORDINARY SHARES OF 1 PENCE



5. The amount by which the block scheme has been increased, if the scheme has 
been increased since the date of the last return:    NIL



6. Number of securities issued/allotted under scheme during period:  NIL



7. Balance under scheme not yet issued / allotted at end of period

                                         159,660 ORDINARY SHARES OF 1 PENCE



8. Number and class of securities originally listed and the date of admission

                                         400,000 ORDINARY SHARES OF 1 PENCE


9. Total number of securities in issue at the end of the period
                                         
                                         51,180,893 ORDINARY SHARES OF 1 PENCE

Name of contact                          ZOE MCGOWAN


Address of contact                       CORPUS CHRISTI HOUSE, 9 WEST STREET,
                                         GODMANCHESTER


Telephone number of contact              01480 437697


Signed by

Director/company secretary/suitably experienced employee/duly authorised 
officer,
for and on behalf of


Name of applicant        PHYTOPHARM PLC


If you knowingly or recklessly give false or misleading information you may be
liable to prosecution.





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