Blocklisting Interim Review

Phytopharm PLC
17 March 2006

                    
                    BLOCKLISTING SIX MONTHLY REVIEW


1. NAME OF COMPANY:       PHYTOPHARM PLC



2. NAME OF SCHEME: THE PHYTOPHARM 1996 UNAPPROVED DISCRETIONARY SHARE OPTION



3. PERIOD OF RETURN:     FROM:  17TH SEPTEMBER 2005  TO: 16TH MARCH 2006



4. NUMBER AND CLASS OF SHARE(S)
   (AMOUNT OF STOCK/DEBT SECURITY)
   NOT ISSUED UNDER SCHEME
   AT END OF THE LAST PERIOD:    140,712 ORDINARY SHARES OF 1 PENCE



5. NUMBER OF SHARES ISSUED/ALLOTTED
   UNDER SCHEME DURING PERIOD:          NIL



6. BALANCE UNDER SCHEME NOT YET ISSUED/ALLOTTED 
   AT END OF PERIOD:                    140,712 ORDINARY SHARES OF 1 PENCE



7. NUMBER AND CLASS OF SHARE(S) 
   (AMOUNT OF STOCK/DEBT SECURITIES) 
   ORIGINALLY LISTED AND THE DATE OF ADMISSION:  400,000 ORDINARY SHARES OF
                                                 1 PENCE ON 16TH MARCH 2004 


PLEASE CONFIRM TOTAL NUMBER OF SHARES IN ISSUE AT THE END OF THE PERIOD
IN ORDER FOR US TO UPDATE OUR RECORDS.

           TOTAL SHARES IN ISSUE 51,180,893 ORDINARY SHARES OF 1 PENCE AT
           16TH MARCH 2006

CONTACT FOR QUERIES

NAME:   ZOE MCGOWANG

TELEPHONE:  [phone]





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