Director/PDMR Shareholding

Phytopharm PLC 06 August 2007 NOTIFICATION OF TRANSACTIONS OF DIRECTORS, PERSONS DISCHARGING MANAGERIAL RESPONSIBILITY OR CONNECTED PERSONS This form is intended for use by an issuer to make a RIS notification required by DR 3.1.4R(1. (1) An issuer making a notification in respect of a transaction relating to shares or debentures of the issuer should complete boxes 1 to 16, 23 and 24. (2) An issuer making a notification in respect of a derivative relating to the shares of the issuer should complete boxes 1 to 4, 6, 8, 13, 14, 16, 23 and 24. (3) An issuer making a notification in respect of options granted to a director/person discharging managerial responsibilities should complete boxes 1 to 3 and 17 to 24. (4) An issuer making a notification in respect of a financial instrument relating to the shares of the issuer (other than a debenture) should complete boxes 1 to 4, 6, 8, 9, 11, 13, 14, 16, 23 and 24. Please complete all relevant boxes in block capital letters. 1. Name of the issuer 2. State whether the notification relates to (i) a transaction notified in accordance with DR 3.1.4R(1)(a); or PHYTOPHARM PLC (ii) DR 3.1.4(R)(1)(b) a disclosure made in accordance with section 324 (as extended by section 328) of the Companies Act 1985; or (iii) both (i) and (ii) NOTIFICATION RELATES TO (iii) 3. Name of person discharging 4. State whether notification managerial responsibilities/ relates to a person connected director with a person discharging managerial responsibilities/ director named in 3 and identify the connected person MR PIERS MORGAN AS 3 ABOVE 5. Indicate whether the notification 6. Description of shares (including is in respect of a holding of the class), debentures or derivatives person referred to in 3 or 4 or in or financial instruments relating respect of a non-beneficial to shares: interest AS 3 ABOVE OPTIONS OVER ORDINARY SHARES OF 1 PENCE EACH 7. Name of registered shareholder(s) 8. State the nature of the and, if more than one, the number transaction of shares held by each of them 9. Number of shares, debentures or 10. Percentage of issued class financial instruments relating to acquired (treasury shares of that shares acquired class should not be taken into account when calculating percentage) 11. Number of shares, debentures or 12. Percentage of issued class financial instruments relating to disposed (treasury shares of that shares disposed class should not be taken into account when calculating percentage) 13. Price per share or value of 14. Date and place of transaction transaction 15. Total holding following 16. Date issuer informed of notification and total percentage transaction holding following notification (treasury shares of that class should not be taken into account when calculating percentage) If a person discharging managerial responsibilities has been granted options by the issuer complete the following boxes 17. Date of grant 18. Period during which or date on which it can be exercised 3 AUGUST 2007 3 AUGUST 2009 TO 2 AUGUST 2017 19. Total amount paid (if any) for grant of 20. Description of shares or the option debentures involved (class and number) NIL 65,000 PHYTOPHARM PLC ORDINARY 1 PENCE SHARES 21. Exercise price (if fixed at the time of 22. Total number of shares or grant) or indication that price is to be debentures over which fixed at the time of exercise options held following notification ONE PENCE PER SHARE 315,000 23. Any additional information 24. Name of contact and telephone number for queries THE OPTION IS SUBJECT TO PERFORMANCE ZOE MCGOWAN CONDITIONS MEASURING THE COMPANY'S TOTAL 01480 437697 SHAREHOLDER RETURN (TSR) AGAINST THE TSR OF THE FTSE SMALLCAP INDEX COMMENCING ON THE GRANT DATE. Name and signature of duly authorised officer of issuer responsible for making notification ___ZOE MCGOWAN_________________________________________________________ Date of notification _6 AUGUST 2007____________________________________ This information is provided by RNS The company news service from the London Stock Exchange

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