Director Shareholding

Phytopharm PLC
06 December 2002

                                  SCHEDULE 11

          NOTIFICATION OF INTERESTS OF DIRECTORS AND CONNECTED PERSONS


1      Name of Company

       Phytopharm PLC

2      Name of Director

       DR S C Loach

3      Please state whether notification indicates that it is in respect of holding of the shareholder named
       in 2 above or in respect of a non beneficial interest or in the case of an individual holder if it is
       a holding of that person's spouse or children under the age of 18 or in respect of a non-beneficial
       interest

       As 2 above

4      Name of the registered holder(s) and, if more than one holder, the number of shares held by each of
       them (if notified)
       As 2 above

5      Please state whether notification relates to a person(s) connected with the Director named in 2 above
       and identify the connected person(s)
       As 2 above

6      Please state the nature of the transaction. For PEP transactions please indicate whether general/
       single co PEP and if discretionary/non discretionary

       Grant of Options (see box 17)


       If a director has been granted options by the company please complete the following boxes


17     Date of grant

       6 December 2002

18     Period during which or date on which exercisable

       5,855 from 7 December 2005 to 6 December 2009

       5,854 from 7 December 2007 to 6 December 2009

19     Total amount paid (if any) for grant of the option
       Nil

20     Description of shares or debentures involved: class, number
       11,709 Ordinary 1 pence shares

21     Exercise price (if fixed at time of grant) or indication that price is to be fixed at time of exercise

       £1.165

22     Total number of shares or debentures over which options held following this notification

       146,152

23     Any additional information



24     Name of contact and telephone number for queries

       S Loach 01480 437697

25     Name and signature of authorised company official responsible for making this notification

       S Loach

26     Date of Notification

       6 December 2002



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