Directors' Dealings

Phytopharm PLC
20 December 1999



  NOTIFICATION OF INTERESTS OF DIRECTORS AND CONNECTED
                         PERSONS
                            
                            
Phytopharm plc announces that the following options  were
granted  to  three  directors  of  the  Company  on  16th
December,  1999.  The cost of the grant of these  options
was nil.


The Schemes referred to are:-


The Phytopharm Share Option Scheme (PSOS)
The Phytopharm 1996 Share Option Plan (1996 SOP)
The Phytopharm 1996 Unapproved Discretionary Share Option
Scheme (1996UDSOS)



Dr. R.P. Dixey

Scheme    Previous    Granted     Current
                      16 Dec 99
                                  
PSOS        540,000        -        540,000
1996SOP        -           -            -
1996UDSOS   111,500        -        111,500
            144,445        -        144,445
               -        17,127       17,127
            126,600        -        126,600
            144,444        -        144,444
               -        17,127       17,127
Grand                             
Total     1,066,989     34,254    1,101,243
                                  

          Exercise                Exercise
          Period                  Price
          From        To          
          17/04/1999  16/04/2003  £0.2625
               -           -            -
          24/04/1999  23/04/1999  £1.9250
          07/12/2000  06/12/2004  £0.4500
          17/12/2002  16/12/2006  £3.8900
          24/04/2001  23/04/2003  £1.9250
          07/12/2002  06/12/2004  £0.4500
          17/12/2004  06/12/2006  £3.8900
                                  
                                  




Dr. S.C. Loach

Scheme    Previous    Granted     Current
                      16 Dec 99
                                  
PSOS        130,000        -        130,000
1996SOP      17,000        -         17,000
1996SOP         555        -            555
1996UDSOS    58,100        -         58,100
             75,279        -         75,279
               -        9,769         9,769
            107,900        -        107,900
             75,833        -         75,833
               -         9,768        9,768
Grand                             
Total       464,667     19,537      484,204


          Exercise                Exercise
          Period                  Price
          From        To          
          17/04/1999  16/04/2003  £0.2625
          24/04/1999  23/04/2006  £1.9250
          07/12,2000  06/12/2007  £0.4500
          24/04/1999  23/04.2003  £1.9250
          17/12/2002  06/12/2004  £0.4500
          17/12/2002  16/12/2006  £3.8900
          24/04/2001  23/04/2003  £1.9250
          07/12/2002  06/12/2004  £0.4500
          17/12/2004  16/12/2006  £3.8900
                                  


Ms. J.E. Allan


Scheme    Previous    Granted     Current
                      16 Dec 99
                                  
PSOS           -           -            -
1996SOP      16,000        -         16,000
              4,444        -          4,444
1996UDSOS    39,045        -         39,045
               -      37,500         37,500
             18,000        -         18,000
             43,489        -         43,489
               -      37,500         37,500
Grand                             
Total       120,978     75,000      195,978

          Exercise                Exercise
          Period                  Price
          From        To          
               -           -            -
          24/04/1999  23/04/2006  £1.9250
          07/12/2000  06/12/2007  £0.4500
          07/12/2000  06/12/2004  £0.4500
          17/12/2002  16/12/2006  £3.8900
          24/04/2001  23/04/2003  £1.9250
          07/12/2002  16/12/2004  £0.4500
          17/12/2004  16/12/2006  £3.8900