Holding in Company

Phytopharm PLC
15 September 2000

Phytopharm plc ('the Company')

Notification of Major Interests in Shares

The Company received a notification from M&G Investment Management Limited
today, informing them that the notifiable interest of Prudential plc, is
2,012,500 shares, representing 5.58% of the issued ordinary share capital of the
Company.