Holding(s) in Company

Phytopharm PLC
15 October 2002



Phytopharm PLC ( the 'Company')

Notification of Major Interests in Shares

The Company received a notification on 11 October 2002 from AMVESCAP PLC,
informing it that, INVESCO Perpetual Income Fund has an interest in 1,659,440
ordinary 1p shares, representing 4.3% of the issued ordinary share capital of
the Company. The shares are registered in the name of Vidacos Nominees Limited.

15 October, 2002


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