Holding(s) in Company

Phytopharm PLC
5 June 2003

Phytopharm PLC (the 'Company')

5 June 2003

Notification of major interests in shares

The Company received notification today from HBOS PLC ('HBOS') that HBOS and its
subsidiary companies have an interest in 1,172,818 Ordinary 1p Shares. This
represents 3.03% of the issued share capital of the Company. Details of that
interest, together with a breakdown between registered holders, are set out
below:-

HSBC Global Custody Nominees (UK) Ltd                       1,171,408 
JP Morgan Chase Bank, Luxembourg                                1,410



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