Holding(s) in Company

Phytopharm PLC
11 October 2004




In accordance with Section 198-202 of the UK Companies Act 1985, Polygon
Investment Partners LLP and Polygon Investment Partners LP, which act on behalf
of Polygon Opportunities Master Fund, informed us on 11th October 2004 that they
have a notifiable interest in 1,500,000 ordinary shares of Phytopharm plc,
amounting to 3.51%%, on the basis of Phytopharm's current issued share capital 
of 42,748,824 ordinary shares.





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