Holding(s) in Company

Phytopharm PLC
19 May 2006



Re: Disclosure of Interest in Shares

In accordance with Section 198 of the Companies Act 1985 Invesco Perpetual
informed us on: 17 May 2006 that following the purchase of 262,500 Ordinary 1
pence shares, INVESCO Perpetual UK Investment Series (UK ICVC) is the
beneficial owner of 8,213,264 Ordinary 1 pence shares of Phytopharm plc
representing 16.04% of the issued share capital. The shares are registered in
the name of Vidacos Nominees Limited.

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