Holding(s) in Company

Phytopharm PLC
02 April 2008



TR-1: notification of major interests in shares

1. Identity of the issuer or the underlying                Phytopharm plc
issuer of existing shares to which voting rights are attached:

2. Reason for the notification (please tick the appropriate box or
boxes)                                                                      

An acquisition or disposal of voting rights                                

An acquisition or disposal of financial instruments which may result in the 
acquisition of shares already issued to which voting rights areattached

An event changing the breakdown of voting rights                            YES

Other (please specify):___________________________________________           

3. Full name of person(s) subject to the                  Deutsche Bank AG
notification obligation:                                

4. Full name of shareholder(s) (if different
from 3.):                                               

5. Date of the transaction (and date on which                   N/A
the threshold is crossed or reached if                  -
different)

6. Date on which issuer notified:                             01/04/08

7. Threshold(s) that is/are crossed or reached:                  3%
                            
8. Notified details:

A: Voting rights attached to shares
Class/type of  Situation previous to the Resulting situation after the
shares         Triggering transaction    triggering transaction
if possible
using the ISIN Number of    Number of    Number  Number of       % of voting
CODE           Shares       Voting       of      voting rights   rights
                            Rights       shares
                                         Direct  Direct Indirect Direct Indirect
                                                 x      xi
Ordinary 1
Pence           1,877,690    1,877,690   Below   Below       -   Below       -
                                         3%      3%              3%
GB000686972

B: Financial Instruments
Resulting situation after the triggering transaction
Type of     Expiration Exercise/     Number of voting rights that may   % of
financial   date       Conversion    be acquired if the instrument is   voting
instrument             Period/ Date  exercised/ converted.              rights


Total (A+B)
Number of voting rights         % of voting rights
Below 3%                         Below 3%

9. Chain of controlled undertakings through which the voting rights and/or the
financial instruments are effectively held, if applicable:


Proxy Voting:
10. Name of the proxy holder:

11. Number of voting rights proxy holder will cease to hold:

12. Date on which proxy holder will cease to hold voting rights:

13. Additional           Notification using the total voting rights figure of
information:             94,544,038

14. Contact name:        Zoe McGowan, Company Secretary

15. Contact
telephone
number:                  01480 437697




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