Holding(s) in Company

Phytopharm PLC
04 April 2008




TR-1: Notification of major interests in shares

1. Identity of the issuer or the underlying                Phytopharm plc
issuer of existing shares to which voting rights        
are attached:

2. Reason for the notification (please tick the 
appropriate box or boxes)                                                                      

An acquisition or disposal of voting rights                     YES
                             
An acquisition or disposal of financial 
instruments which may result in      
the acquisition of shares already issued 
to which voting rights are attached

An event changing the breakdown of voting rights                             
                             
Other (please specify): Placing                                             
                              
3. Full name of person(s) subject to the            Woodbourne Nominees Limited
notification obligation:                                

4. Full name of shareholder(s) (if different                    N/A
from 3.):                                               

5. Date of the transaction (and date on which                 01/04/08
the threshold is crossed or reached if                  
different)

6. Date on which issuer notified:                             02/04/08
                       
7. Threshold(s) that is/are crossed or reached:                   4%
                             
8. Notified details:

A: Voting rights attached to shares

Class/type  Situation        Resulting situation after the triggering
of shares   previous to the  transaction
            Triggering
            transaction
if possible
using the   Number Number of Number of    Number of voting      % of voting
ISIN CODE   of     Voting    shares       rights                rights
            Shares Rights
                             Direct       Direct x     Indirect Direct  Indirect
                                                       xi
Ordinary 1
Pence       Nil    Nil        3,966,000   3,966,000    Nil       4.19%  Nil
GB000686972

B: Financial Instruments

Resulting situation after the triggering transaction

Type of     Expiration Exercise/     Number of voting rights that may   % of
financial   date       Conversion    be acquired if the instrument is   voting
instrument             Period/ Date  exercised/ converted.              rights


Total (A+B)

Number of voting rights                      % of voting rights

3,966,000                                     4.19%

9. Chain of controlled undertakings through which the voting rights and/or the
financial instruments are effectively held, if applicable:

Proxy Voting:

10. Name of the proxy holder:

11. Number of voting rights proxy holder will cease to hold:

12. Date on which proxy holder will cease to hold voting rights:

13. Additional information:                Notification using the total voting 
                                           rights figure of 94,544,038

                                           Holding includes shares formerly 
                                           included within the interest of
                                           Chakra Limited

14. Contact name:                          Zoe McGowan, Company Secretary

15. Contact telephone number:              01480 437697




                      This information is provided by RNS
            The company news service from the London Stock Exchange