Holding(s) in Company

Phytopharm PLC
17 December 2004

In accordance with Section 198-202 of the UK Companies Act 1985, Deutsche Bank 
AG informed us on 15th December 2004 that it and its subsidiary companies no 
longer have a notifiable interest in the ordinary shares of Phytopharm plc on 
the basis of an issued share capital of 42,748,824 ordinary shares.             



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