Holding(s) in Company

Phytopharm PLC
13 May 2005


Re: Disclosure of interests in shares

In accordance with Section 198-202 of the UK Companies Act 1985, Legal & General
Group plc informed us on 13th May 2005 that it and its subsidiary companies have
a notifiable interest in 1,760,787 ordinary shares of Phytopharm plc, amounting
to 3.44%, on the basis of Phytopharm's current issued share capital of
51,180,893 ordinary shares.

                                                              Number of
Registered Holder:                                          Shares Held

HSBC Global Custody Nominee (UK) Ltd A/C 914945                  15,437
HSBC Global Custody Nominee (UK) Ltd A/C 775245                 225,562
HSBC Global Custody Nominee (UK) Ltd A/C 357206               1,254,607
HSBC Global Custody Nominee (UK) Ltd A/C 747381                 108,823
HSBC Global Custody Nominee (UK) Ltd A/C 866203                  83,671
HSBC Global Custody Nominee (UK) Ltd A/C 916681                   2,375
HSBC Global Custody Nominee (UK) Ltd A/C 360509                  70,312
                                                               
Total                                                         1,760,787

Dr Wang Chong 
Chief Financial Officer



                      This information is provided by RNS
            The company news service from the London Stock Exchange