Holding(s) in Company

JPMorgan Fleming American IT PLC
20 April 2006

                                  SCHEDULE 10

                   NOTIFICATION OF MAJOR INTERESTS IN SHARES


1)   Name of company

JPMORGAN FLEMING AMERICAN INVESTMENT TRUST PLC

2)   Name of shareholder having a major interest

RENSBURG SHEPPARDS PLC

3)   Please state whether notification indicates that it is in respect of
     holding of the shareholder named in 2 above or in respect of a
     non-beneficial interest or in the case of an individual holder if it is a
     holding of that person's spouse or children under the age of 18

AS ABOVE

4)   Name of the registered holder(s) and, if more than one holder, the
     number of shares held by each of them

NOT NOTIFIED


5)   Number of shares/amount of stock acquired

N/A

6)   Percentage of issued class

N/A

7)   Number of shares/amount of stock disposed

NOT NOTIFIED

8)   Percentage of issued class

NOT NOTIFIED

9)   Class of security

ORDINARY 25P SHARES

10)  Date of transaction

13 APRIL 2006

11)  Date company informed

20 APRIL 2006

12)  Total holding following this notification

4,575,920

13)  Total percentage holding of issued class following this notification

10.57%

14)  Any additional information

N/A

15)  Name of contact and telephone number for queries

NICOLA WALTERS    020 7742 6000

16)  Name and signature of authorised company official responsible for
     making this notification



ANDREW NORMAN



Date of notification: 20 APRIL 2006






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