Major Interests in Shares

The MedicX Fund Limited
25 April 2008



TR-1(i):             NOTIFICATION OF MAJOR INTERESTS IN SHARES 


1. Identity of the issuer or the underlying issuer of existing             Medicx Fund Limited
shares to which voting rights are attached(ii):


2. Reason for the notification     (please tick the appropriate box or boxes)


An acquisition or disposal of voting rights                                                      Yes


An acquisition or disposal of financial instruments which may result in the acquisition of       No
shares already issued to which voting rights are attached


An event changing the breakdown of voting rights                                                 No


Other (please specify): Conversion of C Shares                                                   No



3. Full name of person(s) subject to the notification obligation      Rensburg Sheppards Investment Management
(iii):                                                                                  Limited


4. Full name of shareholder(s) (if different from 3.)(iv):                                    N/A


5. Date of the transaction (and date on which the threshold is                 23rd April 2008
crossed or reached if different)(v):


6. Date on which issuer notified:                                              25th April 2008


7. Threshold(s) that is/are crossed or reached:                                      20%


8. Notified details:                                                          Nominee Holdings


A: Voting rights attached to shares

Class/type of shares Situation previous to Resulting situation after the triggering transaction(vii)
                     the Triggering
if possible using    transaction (vi)
the ISIN CODE        Number of  Number of  Number of   Number of voting rights  % of voting rights
                     Shares     Voting     shares      ix
                                Rights
                                viii       Direct      Direct  x   Indirect xi  Direct     Indirect

Ordinary Shares           15,252,376                               15,934,610              20.01%

GG00B1DVQL92




B: Financial Instruments

Resulting situation after the triggering transaction xii

Type of financial    Expiration date Exercise/ Conversion      Number of voting rights    % of voting
instrument           xiii            Period/ Date xiv          that may be acquired if    rights
                                                               the instrument is
                                                               exercised/ converted.





Total (A+B)

Number of voting rights                            % of voting rights

15,934,610                                         20.01%




9. Chain of controlled undertakings through which the voting rights and/or the 
financial instruments are effectively held, if applicable xv:

Client holdings registered in the name of Nomimee companies 100% owned by
Rensburg Sheppards Investment Management Limited


Proxy Voting:


10. Name of the proxy holder:                                           N/A

11. Number of voting rights proxy holder will cease to hold:            N/A

12. Date on which proxy holder will cease to hold voting rights:        N/A



13. Additional information:                  N/A



14. Contact name:                            N/A


15. Contact telephone number:                N/A







ANNEX NOTIFICATION OF MAJOR INTERESTS IN SHARES


A. Identity of the person or legal entity subject to the notification obligation

Full Name (including legal form for legal   Rensburg Sheppards Investment
entities)                                   Management Limited


Contact address (registered office for      Quayside House
legal entities)                             Canal Wharf
                                            Leeds   LS11 5PU


Phone number                                0113 236 4171


Other useful information (at least legal    Mike Rigby
representative for legal persons)           (Head of Compliance)



B. Identity of notifier, if applicable


Full Name                                   Philip Martin Beardwell


Contact address                             2 Gresham Street
                                            London
                                            EC2V 7QN


Phone number                                020 7597 1356


Other useful information (eg functional     Senior Compliance Manager
relationship with the person or legal
entity subject to the notification
obligation)


C. Additional information

This disclosure is made by Rensburg Sheppards Investment Management Limited
based on Nominee holdings in accordance with DTR 5.2.1. (F)



Notes

--------------------------




(i)               This form is to be sent to the issuer or underlying issuer and
to be filed with the competent authority.


(ii)               Either the full name of the legal entity or another method
for identifying the issuer or underlying issuer, provided it is reliable and
accurate.


(iii)              This should be the full name of (a) the shareholder; (b) the
person acquiring, disposing of or exercising voting rights in the cases provided
for in DTR5.2.1 (b) to (h);  (c) all the parties to the agreement referred to in
DTR5.2.1 (a), or (d) the direct or indirect holder of financial instruments
entitled to acquire shares already issued to which voting rights are attached,
as appropriate.

In relation to the transactions referred to in points DTR5.2.1 (b) to (h), the
following list is provided as indication of the persons who should be mentioned:

-               in the circumstances foreseen in  DTR5.2.1 (b), the person that
acquires the voting rights and is entitled to exercise them under the agreement
and the natural person or legal entity who is transferring temporarily for
consideration the voting rights;

-               in the circumstances foreseen in DTR 5.2.1 (c), the person
holding the collateral, provided the person or entity controls the voting rights
and declares its intention of exercising them, and person lodging the collateral
under these conditions;

-               in the circumstances foreseen in DTR5.2.1(d), the person who has
a life interest in shares if that person is entitled to exercise the voting
rights attached to the shares and the person who is disposing of the voting
rights when the life interest is created;

-               in the circumstances foreseen in DTR5.2.1 (e), the parent
undertaking and, provided it has a notification duty at an individual level
under DTR 5.1, under DTR5.2.1 (a) to (d) or under a combination of any of those
situations, the controlled undertaking;

-               in the circumstances foreseen in DTR5.2.1 (f), the deposit taker
of the shares, if he can exercise the voting rights attached to the shares
deposited with him at his discretion, and the depositor of the shares allowing
the deposit taker to exercise the voting rights at his discretion;

-               in the circumstances foreseen in DTR5.2.1 (g), the person  that
controls the voting rights;

-               in the circumstances foreseen in DTR5.2.1 (h), the proxy holder,
if he can exercise the voting rights at his discretion, and the shareholder who
has given his proxy to the proxy holder allowing the latter to exercise the
voting rights at his discretion.


(iv)              Applicable in the cases provided for in DTR 5.2.1 (b) to (h).
This should be the full name of the shareholder or holder of financial
instruments who is the counterparty to the natural person or legal entity
referred to in DTR5.2.


(v)               The date of the transaction should normally be, in the case of
an on exchange transaction, the date on which the matching of orders occurs; in
the case of an off exchange transaction, date of the entering into an agreement.


The date on which threshold is crossed should normally be the date on which the
acquisition, disposal or possibility to exercise voting rights takes effect (see
DTR 5.1.1R (3)). For passive crossings, the date when the corporate event took
effect.(DEL: :DEL)

These dates will usually be the same unless the transaction is subject to a
condition beyond the control of the parties.


(vi)              Please refer to the situation disclosed in the previous
notification, In case the situation previous to the triggering transaction was
below 3%, please state 'below 3%'.

vii If the holding has fallen below the minimum threshold , the notifying party
should not be obliged to disclose the extent of the holding, only that the new
holding is less than 3%.


For the case provided for in DTR5.2.1(a), there should be no disclosure of
individual holdings per party to the agreement unless a party individually
crosses or reaches an Article 9 threshold. This applies upon entering into,
introducing changes to or terminating an agreement.

viii                   Direct and indirect

ix              In case of combined holdings of shares with voting rights
attached 'direct holding' and voting rights 'indirect holdings', please split
the voting rights number and percentage into the direct and indirect columns-if
there is no combined holdings, please leave the relevant box blank.

X              Voting rights attached to shares in respect of which the
notifying party is a direct shareholder  (DTR 5.1)

xi                     Voting rights held by the notifying party as an indirect
shareholder (DTR 5.2.1)

xii             If the holding has fallen below the minimum threshold, the
notifying party should not be obliged to disclose the extent of the holding,
only that the new holding is below 3%.

xiii             date of maturity / expiration of the finical instrument i.e.
the date when the right to acquire shares ends.

xiv                   If the financial instrument has such a period-please
specify the period- for example once every three months starting from the (date)

xv             The notification should include the name(s) of the controlled
undertakings through which the voting rights are held. The notification should
also include the amount of voting rights and the percentage held by each
controlled undertaking, insofar as individually the controlled undertaking holds
3% or more, and insofar as the notification by the parent undertaking is
intended to cover the notification obligations of the controlled undertaking.

xvi             This annex is only to be filed with the competent authority.

xvii            Whenever another person makes the notification on behalf of the
shareholder or the natural person/legal entity  referred to in DTR5.2 and
DTR5.3.





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