Director/PDMR Shareholding

Oxford Biomedica PLC
03 April 2007

                                        
                      Oxford BioMedica plc ('the Company')


                Directors' Interest in Shares and Share Options


Oxford BioMedica (OXB:L) The Company today announced that on 3 April 2007 the
following awards under the Oxford BioMedica plc Long Term Incentive Plan (LTIP)
were made to six executive directors. The LTIP was approved by shareholders at
an Extraordinary General Meeting on 1 February 2007.

                                             LTIP: number  Total shares over   Percentage of
                                             of shares     which options are   issued shares under
                                             awarded       held (note 1)       option

Alan Kingsman                                735,533       1,313,533           0.25%
Susan Kingsman                               602,691       1,077,691           0.20%
Michael McDonald                             722,801       2,070,301           0.39%
Peter Nolan                                  547,955       1,106,659           0.21%
Andrew Wood                                  694,379       1,595,923           0.30%
Nick Woolf                                   560,161       1,646,285           0.31%


Note 1: The total shares over which options are held (share options and LTIPs)
following the awards described above.


The share price on which the awards were calculated was 45.25p (the closing
price on the day preceding the awards). The LTIP awards are nil-cost options.
The LTIP awards are subject to a three year holding period, and are exercisable
on the third anniversary of the award, subject to the satisfaction of
performance conditions.



Andrew Wood

Company Secretary, Oxford BioMedica plc

3 April 2007



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