Director Shareholding

Oxford Biomedica PLC
1 November 2001


                       Oxford BioMedica ('the Company')


                             Director's Dealings


Pursuant to the announcement made on 29 May 2001 regarding Dr. Doug Jolly's
subscription for 50,000 shares of 1p each ('Ordinary Shares') the Company
announces that on Friday 26 October 2001 it allotted the 50,000 Ordinary
Shares at a subscription price of 53.5 pence per share to Dr. Doug Jolly, CEO
of the Company's US operation, BioMedica Inc.

Following this allotment Dr. Jolly is interested in 50,000 Ordinary Shares,
representing 0.02% of the Company's current issued ordinary share capital.

Application for the listing of the Ordinary Shares has been made and admission
to listing is expected on Tuesday 6 November 2001.


FURTHER INFORMATION

Andrew Wood, Oxford BioMedica     01865 783000



1 November 2001