Director Shareholding

Oxford Biomedica PLC
23 October 2003


                                                      SCHEDULE 11

                              NOTIFICATION OF INTERESTS OF DIRECTORS AND CONNECTED PERSONS
1)       Name of company
         Oxford Biomedica Plc

2)       Name of director
         Dr. Alan Kingsman

3)       Please state whether notification indicates that it is in respect of holding of the shareholder named in 2
         above or in respect of a non-beneficial interest or in the case of an individual holder if it is a holding of
         that person's spouse or children under the age of 18 or in respect of a non-beneficial interest
         Dr. Alan Kingsman.

4)       Name of the registered holder(s) and, if more than one holder, the number of shares held by each of them (if
         notified)

         Dr. Alan Kingsman.

5)       Please state whether notification relates to a person(s) connected with the Director named in 2 above and
         identify the connected person(s)
         N/A

6)       Please state the nature of the transaction. For PEP transactions please indicate whether general/single co PEP
         and if discretionary/non discretionary
         Sale of nil paid rights

7)       Number of shares/amount of stock acquired
         N/A

8)       Percentage of issued class
         N/A

9)       Number of shares/amount of stock disposed
         3,000,000 Ordinary nil paid rights

10)      Percentage of issued class
         2.3% of the Rights shares

11)      Class of security
         Ordinary nil paid rights

12)      Price per share
         1p

13)      Date of transaction
         21 October 2003

14)      Date company informed
         21 October 2003

15)      Total holding following this notification
         8,603,451

16)      Total percentage holding of issued class following this notification
         3.58%

If a director has been granted options by the company please complete the following boxes

17)      Date of grant

18)      Period during which or date on which exercisable

19)      Total amount paid (if any) for grant of the option

20)      Description of shares or debentures involved: class, number

21)      Exercise price (if fixed at time of grant) or indication that price is to be fixed at time of exercise

22)      Total number of shares or debentures over which options held following this notification

23)      Any additional information
          The resultant holding is based on his existing holding on the current issued share capital which includes some
         shares which are jointly held with spouse and some which are held on behalf of a minor.
24)      Name of contact and telephone number for queries
         Andrew Wood
25)      Name and signature of authorised company official responsible for making this notification
         Andrew Wood

Date of Notification 23 October 2003



                                  SCHEDULE 11

          NOTIFICATION OF INTERESTS OF DIRECTORS AND CONNECTED PERSONS
1)       Name of company
         Oxford Biomedica Plc

2)       Name of director
         Dr. Susan Kingsman

3)       Please state whether notification indicates that it is in respect of holding of the shareholder named in 2
         above or in respect of a non-beneficial interest or in the case of an individual holder if it is a holding of
         that person's spouse or children under the age of 18 or in respect of a non-beneficial interest
         Dr. Susan Kingsman

4)       Name of the registered holder(s) and, if more than one holder, the number of shares held by each of them (if
         notified)
         Dr. Susan Kingsman

5)       Please state whether notification relates to a person(s) connected with the Director named in 2 above and
         identify the connected person(s)
         N/A

6)       Please state the nature of the transaction. For PEP transactions please indicate whether general/single co PEP
         and if discretionary/non discretionary
         Sale of nil paid rights

7)       Number of shares/amount of stock acquired
         N/A

8)       Percentage of issued class

         N/A
9)       Number of shares/amount of stock disposed
         3,000,000 Ordinary nil paid rights

10)      Percentage of issued class
         2.3% of the Rights shares

11)      Class of security
         Ordinary nil paid rights

12)      Price per share
         1p

13)      Date of transaction
         21 October 2003

14)      Date company informed
         21 October 2003

15)      Total holding following this notification
         8,739,139

16)      Total percentage holding of issued class following this notification
         3.64%

If a director has been granted options by the company please complete the following boxes

17)      Date of grant

18)      Period during which or date on which exercisable

19)      Total amount paid (if any) for grant of the option

20)      Description of shares or debentures involved: class, number

21)      Exercise price (if fixed at time of grant) or indication that price is to be fixed at time of exercise

22)      Total number of shares or debentures over which options held following this notification

23)      Any additional information
          The resultant holding is based on her existing holding on the current issued share capital which includes some
         shares which are jointly held with her spouse and some which are held on behalf of a minor

24)      Name of contact and telephone number for queries
         Andrew Wood

25)      Name and signature of authorised company official responsible for making this notification
         Andrew Wood

Date of Notification 23 October 2003











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