Holding(s) in Company

Oxford Biomedica PLC
15 July 2004

                                  SCHEDULE 10

                   NOTIFICATION OF MAJOR INTERESTS IN SHARES


1.       Name of company

         Oxford BioMedica Plc

2.       Name of shareholder having a major interest

         Man Financial Limited

3.       Please state whether notification indicates that it is in respect of 
         holding of the shareholder named in 2 above or in respect of a 
         non-beneficial interest or in the case of an individual holder if it is 
         a holding of that person's spouse or children under the age of 18.

         As above

4.       Name of the registered holder(s) and, if more than one holder, the 
         number of shares held by each of them 

         Not disclosed

5.       Number of shares/amount of stock acquired

         Not disclosed

6.       Percentage of issued class

         Not disclosed

7.       Number of shares/amount of stock disposed

         Not disclosed

8.       Percentage of issued class

         Not disclosed

9.       Class of security

         Ordinary shares of 1 pence each

10.      Date of transaction

         14 July 2004

11.      Date company informed

         15 July 2004

12.      Total holding following this notification

         33,111,600

13.      Total percentage holding of issued class following this notification

         8.92%

14.      Any additional information

15.      Name of contact and telephone number for queries

         Andrew Wood 01865 783000

16.      Name of authorised company official responsible for making this 
         notification.

         Andrew Wood, CFO


Date of notification: 15 July 2004



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