Holding(s) in Company

Oxford Biomedica PLC
6 July 2004



                                  SCHEDULE 10

                   NOTIFICATION OF MAJOR INTERESTS IN SHARES


1.       Name of company

         Oxford BioMedica Plc

2.       Name of shareholder having a major interest

         Prelude Trust plc

3.       Please state whether notification indicates that it is in respect of holding of the shareholder
         named in 2 above or in respect of a non-beneficial interest or in the case of an individual holder
         if it is a holding of that person's spouse or children under the age of 18.

         As above

4.       Name of the registered holder(s) and, if more than one holder, the number of shares held by each
         of them

          Not disclosed

5.       Number of shares/amount of stock acquired

         N/A

6.       Percentage of issued class

         N/A

7.       Number of shares/amount of stock disposed

         500,000

8.       Percentage of issued class

         Not disclosed

9.       Class of security

         Ordinary shares of 1 pence each

10.      Date of transaction

         5th July 2004

11.      Date company informed

         6th July 2004

12.      Total holding following this notification

         21,837,346

13.      Total percentage holding of issued class following this notification

         5.88%

14.      Any additional information

15.      Name of contact and telephone number for queries

         Andrew Wood 01865 783000

16.      Name of authorised company official responsible for making this notification.

         Andrew Wood, CFO

Date of notification: 6 July 2004





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