Holding(s) in Company

Oxford Biomedica PLC
25 August 2005


Oxford BioMedica plc (the 'Company')

Notification of Major Interests in Shares

The Company has received notification from Calyon Corporate and Investment Bank
that Credit Agricole Cheuvreux International Ltd has an interest in 37,217,805
Oxford BioMedica plc 1p ordinary shares. This represents 9.9% of the presently
issued share capital of the Company, which stands at 376,676,718 shares.

25 August 2005

Andrew Wood
Chief Financial Officer
Tel [phone]



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