Holding(s) in Company

Oxford Biomedica PLC
19 December 2005


                      Oxford BioMedica plc ('the Company')

                              Holding(s) in Company

The Company was notified on 16 December 2005 by Man Financial Limited ('Man') 
that, following a recent purchase, funds managed by Man are interested in a 
total of 26,719,906 of the Company's ordinary shares of 1p each, representing 
5.36 per cent. of the issued Ordinary Share capital.


19 December 2005






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