Holding(s) in Company

Oxford Biomedica PLC
16 September 2005


Oxford BioMedica plc (the 'Company')

Notification of Major Interests in Shares

The Company has received notification today from Man Financial Limited that at
close of business on 15 September 2005, Man Financial Limited was the beneficial
owner of 22,454,413 Oxford BioMedica plc 1p ordinary shares. This represents
5.95% of the presently issued share capital of the Company.

16 September 2005

Andrew Wood
Chief Financial Officer
Tel. [phone]



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