Holding(s) in Company

Oxford Biomedica PLC
22 May 2006


                      Oxford BioMedica plc (the 'Company')


                              Holdings in Company



The Company was notified on 22 May 2006 by M&G Investment that following recent 
purchases, at 18 May 2006 Prudential  plc and certain of its subsidiary companies 
had a notifiable interest in 20,541,106 of the Company's ordinary shares of 1p each 
('Ordinary Shares'), representing 4.11 per cent. of the issued ordinary share capital.


The Prudential Assurance Company Limited

Registered holder                                          Shares            %
PRUCLT HSBC GIS NOM(UK) PAC AC                         19,700,368         3.94
PRUCLT HSBC GIS NOM(UK) PPL AC                            840,738         0.17
                                      Total            20,541,106         4.11



In the Company's annual report and accounts, dated 11 May 2006, a total holding
of 39,825,426 Ordinary Shares, representing 7.97 per cent. of the Company's
total issued share capital was disclosed for M&G Investment. Following the
recent purchases, this holding now totals a beneficial interest of 41,815,637
Ordinary Shares, representing 8.37 per cent. of the total issued ordinary share
capital.



22 May 2006


Andrew Wood

Chief Financial Officer

Tel. [phone]



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