Holding(s) in Company

Oxford Biomedica PLC
27 February 2007


TR-1(i): NOTIFICATION OF MAJOR INTERESTS IN SHARES


1. Identity of the issuer or the underlying issuer of existing shares to which
   voting rights are attached (ii):


   Oxford BioMedica PLC

2. Reason for the notification (please state Yes/No): ( )

   An acquisition or disposal of voting rights: ( )


   An acquisition or disposal of financial instruments which may result in the
   acquisition of shares already issued to which voting rights are attached: ( )


   An event changing the breakdown of voting rights: ( )


   Other (please specify) : ( Yes )


   Declaration of Major Shareholding as per FSA Transitional Provision 7

3. Full name of person(s) subject to the notification obligation (iii):


   Legal & General Group Plc (L&G)

4. Full name of shareholder(s) (if different from 3.) (iv):


   n/a

5. Date of the transaction (and date on which the threshold is crossed or
   reached if different) (v):


   n/a

6. Date on which issuer notified:


   26 February 2007

7. Threshold(s) that is/are crossed or reached:


   Above 3% (L&G)

8. Notified details:




A: Voting rights attached to shares

Class/type of shares       Situation previous to the Triggering transaction (vi)
if possible using                         
the ISIN CODE
                      Number of shares         Number of voting Rights (viii)


GB0006648157                11,941,885                      11,941,885



Resulting situation after the triggering transaction (vii)


Class/type of shares  Number of shares    Number of voting       % of voting
if possible using                           rights (ix)            rights
the ISIN CODE


                                Direct Direct (x)    Indirect   Direct Indirect
                                                         (xi)


GB0006648157                16,729,883 16,729,883                3.33%


B: Financial Instruments

Resulting situation after the triggering transaction (xii)


Type of     Expiration Date  Exercise/Conversion Number of voting     % of voting
financial   (xiii)           Period/Date (xiv)   rights that may be   rights
instrument                                       acquired if the
                                                 instrument is
                                                 exercised/
                                                 converted.


N/A                     N/A                 N/A                N/A            N/A


Total (A+B)


Number of voting rights  % of voting rights


     16,729,883               3.33%




9. Chain of controlled undertakings through which the voting rights and/or the
   financial instruments are effectively held, if applicable (xv):



Legal & General Group Plc (Direct and Indirect) (Group)



Legal & General Investment Management (Holdings) Limited (LGIMH) (Direct and Indirect)



Legal & General Investment Management Limited (Indirect) (LGIM)



Legal & General Group Plc (Direct) (L&G) (16,729,883 - 3.33% = LGAS, LGPL & PMC)



Legal & General Investment Management      Legal & General Insurance Holdings
(Holdings) Limited (Direct) (LGIMHD)       Limited (Direct) (LGIH)



Legal & General Assurance (Pensions        Legal & General Assurance Society
Management) Limited (PMC)                  Limited (LGAS & LGPL)



                                           Legal & General Pensions Limited
                                           (Direct) (LGPL)


Proxy Voting:



10. Name of the proxy holder:


N/A

11. Number of voting rights proxy holder will cease to hold:


N/A

12. Date on which proxy holder will cease to hold voting rights:


N/A

13. Additional information:


Notification using the total voting rights figure of 501,496,666

First notification under DTR Sourcebook


14. Contact name:

Andrew Wood

15. Contact telephone number:


01865 783000

Annex to Notification Of Major Interests In Shares (xvi)

A: Identity of the person or legal entity subject to the notification obligation

Full name (including legal form for legal entities):


Legal & General Group Plc

Contact address (registered office for legal entities):


Temple Court, 11 Queen Victoria Street, London, EC4N 4TP

Phone number:


020 7528 6742

Other useful information (at least legal representative for legal persons):
Gayle Little


B: Identity of the notifier, if applicable (xvii)

Full name:


Helen Lewis

Contact address:


Bucklersbury House, 3 Queen Victoria Street, London, EC4N 8NH


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