Interest in Share Options

Oxford Biomedica PLC
07 September 2006


                      Oxford BioMedica plc ('the Company')


                           Interest in share options


Oxford BioMedica (OXB:L). The Company today announced that, as part of a grant
of share options to a number of eligible employees, it had granted 209,000
options over 1p ordinary shares under the Oxford BioMedica 1996 (No.1) share
option scheme on 6 September 2006 to Dr Michael McDonald, Chief Medical Officer
who joined the board of the Company in February 2006, and 172,531 to Sharon
Wood, who is an employee of Oxford BioMedica and is the wife of Andrew Wood,
Chief Financial Officer and Company Secretary.

It is the Company's policy to award share options to all UK employees, following
the announcement of full-year or half-year results. The exercise price for the
options is 31.0 pence per share. The options become exercisable three years from
the date of grant and will remain exercisable up to seven years from the date of
grant. The options granted to Dr McDonald are subject to a performance
condition: the options will only be exercisable if at the time of exercise, or
for at least 12 months in the three years before exercise, the percentage
increase in Oxford BioMedica's Total Shareholder Return exceeds the percentage
increase in the FTSE TechMark Mediscience index since the date of grant of the
option.


Following the grant of these options, Dr Michael McDonald has an interest in
options over a total of 1,347,500 of the Company's shares, and Sharon Wood has
an interest in options over 345,062 shares.




Andrew Wood

Company Secretary, Oxford BioMedica plc

7 September 2006



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