Major Interest In Shares

Oxford Biomedica PLC
15 February 2008


For Immediate Release                                           15 February 2008

                              Oxford Biomedica Plc


TR-1: Notifications of Major Interests in Shares

Oxford Biomedica Plc

1. Identity of the issuer or the underlying
issuer of existing shares to which voting
rights are attached:

2. Reason for notification (yes/no)

Yes

An acquisition or disposal of voting rights

An acquisition or disposal of financial instruments which may result
in the acquisition of shares already issued to which voting rights
are attached

An event changing the breakdown of voting rights

Other (please specify):

Cubana Investments Limited

3. Full name of person(s) subject to
notification obligation:

4. Full name of shareholder(s) (if
different from 3):

5. Date of transaction (and date on     12 February 2008
which the threshold is crossed or
reached if different):


6. Date on which issuer notified:       14 February 2008


7. Threshold(s) that is/are crossed or  5%
reached:

8: Notified Details

A: Voting rights attached to shares

Class/type of Situation previous to Resulting situation after the triggering
shares        the triggering        transaction
              transaction
If possible
use ISIN code

              Number of  Number of  Number of   Number of voting     Percentage of
              shares     voting     shares      rights               voting rights
                         rights


                                                Direct      Indirect Direct   Indirect

GB0006648157         -        -   30,597,220  30,597,220             5.70%



B: Financial Instruments

Resulting situation after the triggering transaction

Type of         Expiration date Exercise/          No. of voting       Percentage of
financial                       conversion period/ rights that may be  voting rights
instrument                      date               acquired (if the
                                                   instrument
                                                   exercised/
                                                   converted)


Total (A+B)

Number of voting rights                     Percentage of voting rights


30,597,220                                  5.70%

9. Chain of controlled undertakings through which the voting rights and /or
the financial instruments are effectively held, if applicable:

Proxy Voting:

10. Name of proxy holder:

11. Number of voting rights proxy
holder will cease to hold:

12. Date on which proxy holder will
cease to hold voting rights:

13. Additional information:

14 Contact name:                       Andrew Wood

15. Contact telephone number:          01865 783000



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