Viragen Update

Oxford Biomedica PLC 22 June 2007 FOR IMMEDIATE RELEASE 22 JUNE 2007 Oxford BioMedica viragen update Oxford, UK - 22 June 2007: Oxford BioMedica (LSE: OXB), a leading gene therapy company, today announces that Viragen Inc (AMEX: VRA) has halted development of the OVA(TM) System, Viragen's avian transgenic programme for the manufacture of therapeutic proteins in the whites of eggs laid by transgenic hens as part of its efforts to 'streamline its research focus'. In halting all further development of the OVA(TM) System, Viragen has notified Roslin Institute and Oxford BioMedica of its intent to terminate its research and license agreements, respectively. Professor Alan Kingsman, Oxford BioMedica's Chief Executive Officer commented: 'It is disappointing that Viragen's streamlined research no longer includes investment in the avian transgenic programme. Over the coming weeks Oxford BioMedica and Roslin Institute will be exploring ways to advance this exciting technology, which has come from some truly superb science.' -Ends- For further information, please contact: Oxford BioMedica plc: Professor Alan Kingsman, Chief Executive Tel: +44 (0)1865 783 000 Viragen, Inc: Director of Communications, Doug Calder Tel: (954) 233 8746 City/Financial Enquiries: Lisa Baderoon/ Mark Court/ Mary-Jane Johnson Tel: +44 (0)20 7466 5000 Buchanan Communications Scientific/Trade Press Enquiries: Gemma Bradley/ Holly Griffiths/ Katja Stout Tel: +44 (0)20 3008 7550 Northbank Communications Notes to editors 1. Oxford BioMedica Oxford BioMedica (LSE: OXB) is a biopharmaceutical company specialising in the development and commercialisation of novel therapeutic vaccines and gene-based therapies with a focus on oncology and neurotherapy. The Company was established in 1995 as a spin-out from Oxford University, and is listed on the London Stock Exchange. The Company has a platform of gene delivery technologies, which are based on highly engineered viral systems. Oxford BioMedica also has in-house clinical, regulatory and manufacturing know-how. In oncology, the lead product candidate is TroVax(R), an immunotherapy for multiple solid cancers, which is licensed to sanofi-aventis for global development and commercialisation. A Phase III trial of TroVax in renal cancer is ongoing and sanofi-aventis is implementing a development plan for colorectal cancer. Oxford BioMedica's oncology pipeline includes a specific immunotherapy candidate, Hi-8(R) MEL, for melanoma, which has completed two clinical trials. In neurotherapy, the Company's lead product, ProSavin(R), is expected to enter clinical development for Parkinson's disease in 2007. The neurotherapy pipeline also includes preclinical gene-based therapeutics for vision loss, motor neuron disease and nerve repair. The Company is underpinned by over 80 patent families, which represent one of the broadest patent estates in the field. The Company has a staff of approximately 75 split between its main facilities in Oxford and its wholly owned subsidiary, BioMedica Inc, in San Diego, California. Corporate partners include sanofi-aventis for TroVax and Wyeth for a targeted antibody therapy. The Company also has collaborations with Intervet, Sigma-Aldrich, MolMed and Virxsys. Technology licensees include Merck & Co, Biogen Idec, GlaxoSmithKline and Pfizer. Further information is available at www.oxfordbiomedica.co.uk 2. Avian Transgenics The avian transgenic technology is designed to develop the chicken into a pharmaceutical bioreactor, one that can meet the growing need for protein-based human therapeutics. Based on the creation of lines of transgenic hens which have been engineered to produce a target protein in their eggs using Oxford BioMedica's LentiVector(R) gene delivery system, this technology is being developed as an efficient and economical alternative to standard bio-manufacturing techniques, having many apparent advantages in ease of scale-up, lower costs of production and quality of product produced. 3. Viragen, Inc. With international operations in the US, Scotland and Sweden, Viragen is a biopharmaceutical company engaged in the research, development, manufacture and commercialisation of therapeutic proteins for the treatment of cancers and viral diseases. The product portfolio includes: Multiferon(R) (multi-subtype, human alpha interferon) which is uniquely positioned in valuable niche indications, such as high-risk malignant melanoma, and other select cancers and infectious diseases; VG102, a novel monoclonal antibody that binds selectively to an antigen that is significantly over-expressed on nearly all malignant tumours; and VG106, a novel cytokine targeting difficult-to-treat cancers. For more information, please visit: http://www.Viragen.com This information is provided by RNS The company news service from the London Stock Exchange
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