Directorate Change

Oxford Instruments PLC
18 November 2004


18 November 2004


                             Oxford Instruments plc

                                  Board Change

Oxford Instruments plc, the advanced instrumentation company, today announces
that Dr Andrew Mackintosh, Chief Executive, will be leaving the Group. He
relinquishes his duties as Chief Executive with immediate effect and Nigel Keen,
Chairman, will assume the day-to-day responsibility for running the Group until
a new Chief Executive is appointed.

Nigel Keen commented: "I thank Andrew Mackintosh for the central part he has
played in establishing a strong operational platform across our businesses.
Under his leadership, we have achieved "best in class" in many areas of the
business and have put in place the tools and processes necessary for success in
important disciplines such as supply chain management and new product
innovation. Andrew leaves us in good shape to drive our strategy forward.
"Excellent technological capabilities exist within Oxford Instruments in the
life sciences, nanotechnology and environmental quality control sectors. Our
focus continues to be firmly placed on translating those strengths into
innovative solutions for our customers which will lead the Group to deliver
improved profitability and returns for our shareholders. I look forward to
accelerating the pace of growth and to identifying a new Chief Executive who
will add momentum to the future development of our business."

Oxford Instruments has also announced this morning its Interim Results for the
six months to 30 September 2004.

                                      ENDS

Enquiries:

Oxford Instruments plc              Tel: [phone]
Nigel Keen, Chairman


Hogarth Partnership Limited         Tel: [phone]
Rachel Hirst
Andrew Jaques




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