AACR Presentation Update

Physiomics PLC 08 April 2008 Physiomics plc The Magdalen Centre The Oxford Science Park Robert Robinson Avenue Oxford OX4 4GA UK Tel 01865 784980 Fax 08701 671931 08 April 2008 Physiomics plc ('Physiomics' or 'the Company') Physiomics to present on Cyclacel Pharmaceuticals collaboration on Aurora Kinase research program at the Annual Meeting of American Association of Cancer Research ('AACR') Physiomics plc (AIM: PYC), the Oxford, UK based systems biology company, is pleased to announce that it will be participating in the 2008 AACR Annual Meeting, taking place in San Diego, on 12-16 April 2008. Dr Christophe Chassagnole, Chief Operating Officer of Physiomics, will present the results of a recent collaboration with Cyclacel pharmaceuticals Inc. (NASDAQ: CYCC, NASDAQ: CYCCP). It will be shown how Physiomics technologies have been used to support a pre-clinical research program on a novel Aurora Kinase inhibitor CYC116 that has since entered in a phase 1 clinical research program. The abstract ('Systems biology analysis of a novel Aurora kinase inhibitor: CYC116', No 1645) will be published in the 2008 Proceeding of the AACR and will be presented in the poster session 'Cellular and Molecular Biology 16', scheduled for 8:00 am 12:00 pm on 14 April. More information about the conference may be found at www.aacr.org For further information: Physiomics plc +44 (0)1865 784980 Dr Christophe Chassagnole, COO E-mail: cchassagnole@physiomics-plc.com Grant Thornton Corporate Finance +44 (0)20 7383 5100 Philip Secrett, Colin Aaronson About Physiomics plc Physiomics plc (AIM:PYC) is a computational systems biology services company applying simulations of cell behaviour to drug development to reduce the high attrition rates of clinical trials. As 80-90 per cent of all clinical drug candidates fail to reach the market, estimates1 show that an overall ten per cent improvement in success rates could reduce the cost of one drug's development by as much as $242 million, from the current estimate of around $800 million. Physiomics develops computational systems biology models to predict and understand cancer drug efficacy from pre-clinical research to clinical development. Physiomics has created detailed mathematical models incorporating most important molecular events taking place during the human cell cycle and apoptosis processes. Physiomics developed SystemCell(R) technology, a multi-cellular environment software, which enables the simulation of population of 'virtual cells'. Physiomics, based in Oxford, UK, was founded in 2001, and floated on AIM in 2004. For further information, please visit www.physiomics-plc.com SystemCell(R) is a registered trademark of Physiomics plc 1Tufts Centre Impact Report 2002 This information is provided by RNS The company news service from the London Stock Exchange

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