Notifiable Interest

Proteome Sciences PLC
22 February 2006

Proteome Sciences Plc ('the Company')



22 February 2006



Notifiable Interest



The Company received notification on 21 February 2006 from Fidelity Investments
that FMR Corp. and its direct and indirect subsidiaries, Fidelity International
Limited and its direct and indirect subsidiaries and Mr Edward C. Johnson 3rd (a
principal shareholder of FMR Corp. and Fidelity International), have a
notifiable interest in the ordinary shares of the Company of 12,962,250 shares,
being 9.86% of the current issued ordinary share capital of the Company.



END






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