AGM Statement

Provexis PLC 29 September 2006 Provexis plc ('The Company') Annual General Meeting Statement At Provexis plc's Annual General Meeting to be held this morning, the non-executive Chairman of Provexis plc, Dawson Buck, will give the following statement and update on current trading. 'At the time of the announcement on 15 June 2006 of our results for the year ended 31 March 2006 I was pleased to report considerable progress made by the business. Since the year end the Company has continued to achieve major milestones in its development which unlock significant global commercial opportunities. Sirco Update 'Sales of Sirco for the first-half of the year are on track, and we are pleased with the current distribution level of 1200 outlets, and will continue to develop this customer base. The one-litre chilled pack is on sale in over 800 outlets of major multiple grocers including Tesco, the market leader. I am pleased with the progress made in this highly competitive channel, and indeed we are producing weekly sales comparable with some more established brands. We expect to extend distribution in the multiple grocer channel in the Autumn. 'The 250ml single-serve pack is now available in Holland & Barrett and a range of independent health-food stores, and this format will play a strategic role as we seek distribution in the pharmacy channel over the medium-term. 'National advertising and retailer promotions are playing a significant role in the development of the brand and we estimate that 10 million of our target consumers have seen our advertising more than 8 times in the year to date. We will continue to invest consistently in Sirco in order to maintain and build distribution, while being conscious of our target to move into a positive contribution on a monthly basis during the next year. Licensing Update 'I was pleased to announce the signing of a twelve-month Exclusivity Agreement with a major international brand owner in August. This agreement is proceeding well, and we have made good progress in the joint-development of a new format of our Fruitflow technology, with our partner funding the bulk of the development costs and providing a great deal of resource to us. 'We are now also in licence negotiations with our partner, and subject to certain economic, regulatory and technical hurdles being cleared, we expect to conclude these negotiations in the coming weeks. 'We continue to seek further licence partners in the areas of juice drinks, products for Deep Vein Thrombosis, and dietary supplements and over-the-counter formats. As a longer-term project, we also anticipate exploring medical applications for our products. Fruitflow Technology 'We are intensifying our focus on the development of Fruitflow. The management team believes that this patented, scientifically-proven technology can extend its applicability over a broader range of formats and claim areas, and as such this will be the focus of our efforts and investment over coming months. 'We have early proof of concept work in the area of Deep Vein Thrombosis, and consumer research work carried out by Provexis indicates this is an area of high concern for airline passengers. A patent has been filed for this claim area, and in the coming months we will develop further the scientific proof for this opportunity. 'The original format of Fruitflow is now established commercially, and we will be targeting cost optimisation over the short to medium term. Furthermore, development of the powder version of Fruitflow, in conjunction with our strategic partner, is progressing well and will provide us with a technology applicable to a wide range of food, beverage and medical products. Pipeline 'In the forthcoming year we will concentrate our resources on maximising the value from Fruitflow. However, in addition we will continue to develop the plantain-based extract for the treatment of Crohn's Disease. Human trials and clinical trials are to commence late in 2006 and we expect a first indication of the results of those trials in the second half of 2007. Financial 'As stated, Sirco sales are on track for the first half of the year, and cash is in line with forecast. The management team is focussed on careful management of working capital, and within this a tight control on costs. Summary 'The functional and medical food sector is a strong growth market globally and we are uniquely positioned to capitalise on that opportunity. We therefore look forward to making further progress as we develop Fruitflow and expand our licensing opportunities.' For further information please contact: Stephen Moon, Commercial Director Tel: 020 8392 6634 Provexis plc Emma Kent/ Victoria Geoghegan Tel: 020 7861 3232 Bell Pottinger Corporate & Financial This information is provided by RNS The company news service from the London Stock Exchange

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