Closure of Sirco juice brand

Provexis PLC
02 July 2007

For release at 07.00 Monday July 2nd 2007





                                  PROVEXIS plc
                         ('Provexis' or the 'Company')

                          CLOSURE OF SIRCO JUICE BRAND


Provexis plc (PXS.L), the nutraceutical company that develops
scientifically-proven functional and medical foods, announces that, further to
the preliminary results announcement on 30 May 2007, the Company has undertaken
a strategic review of its Sirco(R) juice brand. In order to facilitate the
negotiation of exclusive rights for potential license partners, the Company is
going to cease production and supply of Sirco(R) with immediate effect. Sirco(R)
is currently distributed in approximately 1,900 major multiple grocers and high
street retailers. There are no financial write-offs related to the closure.


Provexis is in the process of repositioning itself as a pure discovery,
development and licensing business and this closure is a key part of the
implementation phase. The Sirco(R) brand has met its aims in raising awareness
of the Company's patented, scientifically-proven Fruitflow(R) heart-health
technology with global food and beverage brand owners and has demonstrated
consumer demand for the technology, as well as underpinning the implementation
of its regulatory and health claims strategy.


There are four sectors in which Provexis is seeking major partnerships, namely,
food and dairy, juice and juice drinks, products for deep vein thrombosis, and
dietary supplements and medical products. On 30 March 2007, the Company
announced a collaboration with Unilever for certain formats within the food and
dairy sector.


Provexis is currently in discussions with two major global beverage brand owners
regarding potential license arrangements for Fruitflow(R) in juice and juice
drinks and these companies require extensive, exclusive geographical rights,
which the closure of Sirco(R) will facilitate. The Company hopes that these
discussions will reach a satisfactory conclusion in due course.


Stephen Moon, Chief Executive Officer of Provexis plc, commented:


'After examining other possible exit options, it was felt that the long-term
potential of licensing to a major brand owner would deliver higher shareholder
value. We have carefully planned this step and there are no write-offs
associated with it. This completes our programme of structural change and I am
pleased to say we have significantly reduced our monthly cash burn.'



                                     -ends-



For further information please contact:


Stephen Moon, Chief Executive
Provexis plc                                Tel: [phone]


Tom Griffiths/Alasdair Younie               Tel: [phone]
Arbuthnot Securities


Chris Steele
Adventis Financial PR                       Tel: [phone]










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