Director/PDMR Shareholding

Provexis PLC
13 July 2005


PROVEXIS PLC

13 July 2005

Grant of Options

The Board of Provexis plc yesterday approved the grant to Directors of options
over ordinary shares in the Company under the Company's 2005 Share Option
Scheme, exercisable at 5.5p per share any time between 3 and 10 years of the
date of grant, as follows:

                              Options Granted            Total Options held
                                                         following Grant
                              ---------------            ------------------
Stephen Franklin                  2,379,765                 8,251,234
Stephen Moon                      1,294,153                 2,411,773


Ends

For further information please contact:

Provexis plc
Andrew Smithson, Company Secretary 0161 226 5038

Arbuthnot Securities Limited
Tom Griffiths 020 7012 2000

Bell Pottinger Corporate and Financial
Ann-Marie Wilkinson/Emma Kent 020 7861 3232








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